Author

M. T. Weirauch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

L. Kottyan· 2 shared A. Fromowitz· 1 shared A. Kulkarni· 1 shared A. Lynch· 1 shared A. M. Klingler· 1 shared A. T. Dwyer· 1 shared A. Verma· 1 shared A. VonHandorf· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

L. Kottyan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation

M. Venkatasubramanian, L. Schwartz, N. Ramachandra, J. Bennett, K. R. Subramanian, S. Gordon-Mitchell, A. Fromowitz, K. Pradhan, D. Shechter, S. Sahu, D. Heiser, P. Scherle, X. Chen, C. Chetal, A. Kulkarni, , N. G. Salomonis

The paper identifies a splicing mechanism in AML independent of mutations, showing it drives poor prognosis and can be targeted with PRMT5 inhibition.

bioRxiv · Feb 4, 2024Cancer Biology

The transcription factor Zeb2 drives differentiation of age-associated B cells

D. Dai, S. Gu, X. Han, H. Ding, Y. Jiang, X. Zhang, C. Yao, S. Hong, J. Zhang, Y. Shen, G. Hou, B. Qu, H. Zhou, Y. Qin, Y. He, , N. Shen

The paper identifies Zeb2 as a critical transcription factor driving age-associated B-cell differentiation and autoimmunity in humans and mice.

Science · Jan 26, 2024Peer-reviewedImmunology

Lineage tracing of newly accrued nuclei in skeletal myofibers uncovers distinct transcripts and interplay between nuclear populations

C. Sun, C. Swoboda, M. Petrany, S. Parameswaran, A. VonHandorf, M. T. Weirauch, C. Lepper, D. Millay

The paper identifies distinct transcriptional states of newly fused versus pre-existing nuclei in skeletal myofibers and shows their interplay in regulating muscle growth.

bioRxiv · Aug 24, 2023 · PreprintCell Biology

Aryl Hydrocarbon Receptor Suppresses Eosinophilic Esophagitis Responses through OVOL1 and SPINK7

N. P. Azouz, A. M. Klingler, M. Rochman, M. Paul, J. M. Caldwell, M. Brusilovsky, A. T. Dwyer, X. P. Chen, D. Miller, A. Lynch, C. Forney, L. Kottyan, M. T. Weirauch, M. E. Rothenberg

This study identifies OVOL1 as a regulator of SPINK7 expression in eosinophilic esophagitis, showing AHR activation enhances SPINK7 and barrier function while IL-4 and IL-13 inhibit this pathway.

bioRxiv · May 17, 2023 · PreprintImmunology