Author

M. V. Frolov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. B. M. M. K. Islam· 2 shared C. Blaha· 1 shared C. W. McCloskey· 1 shared E. V. Benevolenskaya· 1 shared F. R. Palma· 1 shared G. Cottone· 1 shared G. Ramakrishnan· 1 shared H. Gao· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

A. B. M. M. K. Islam

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2 papers

Recent·Most cited

Metabolic shift to serine pathway induced by lipids confers oncogenic properties in non-transformed breast cells

M. B. Eduardo, G. Cottone, C. W. McCloskey, S. Liu, M. P. Zappia, E. V. Benevolenskaya, A. B. M. M. K. Islam, M. V. Frolov, F. R. Palma, P. Gao, J. Setya, H. Gao, X. Xuei, R. Khokha, J. Locasale, , S. E. Clare

The paper shows that lipid metabolism, specifically through OA, shifts metabolic pathways in breast cells, increasing SAM and 2-HG, which contribute to oncogenic properties and epigenetic changes.

bioRxiv · Feb 21, 2024 · PreprintCancer Biology

Cell autonomous versus systemic Akt isoform deletions uncovered new roles for Akt1 and Akt2 in breast cancer

N. Hay, X. Chen, M. M. Ariss, G. Ramakrishnan, V. Nogueira, C. Blaha, W. Putzbach, A. B. M. M. K. Islam, M. V. Frolov

The paper compares cell autonomous and systemic Akt1/Akt2 deletion effects in breast cancer, finding distinct roles in tumorigenesis and metastasis.

bioRxiv · Jan 8, 2020Cancer Biology