Author

F. R. Palma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

M. G. Bonini· 2 shared A. B. M. M. K. Islam· 1 shared A. Meyer· 1 shared B. N. Gantner· 1 shared C. M. Furdui· 1 shared C. W. McCloskey· 1 shared D. R. Coelho· 1 shared D. R. Spitz· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

M. G. Bonini

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Metabolic shift to serine pathway induced by lipids confers oncogenic properties in non-transformed breast cells

M. B. Eduardo, G. Cottone, C. W. McCloskey, S. Liu, M. P. Zappia, E. V. Benevolenskaya, A. B. M. M. K. Islam, M. V. Frolov, F. R. Palma, P. Gao, J. Setya, H. Gao, X. Xuei, R. Khokha, J. Locasale, , S. E. Clare

The paper shows that lipid metabolism, specifically through OA, shifts metabolic pathways in breast cells, increasing SAM and 2-HG, which contribute to oncogenic properties and epigenetic changes.

bioRxiv · Feb 21, 2024 · PreprintCancer Biology

H3.1Cys96 oxidation by mitochondrial ROS promotes chromatin remodeling, breast cancer progression to metastasis and multi-drug resistance

F. R. Palma, F. T. Ogata, D. R. Coelho, K. Pulakanti, A. Meyer, Y. Huang, J. M. Daves, M. J. Schipma, C. M. Furdui, D. R. Spitz, B. N. Gantner, S. Rao, V. Backman, M. G. Bonini

The paper shows that mitochondrial H2O2 oxidizes H3.1 at Cys96, promoting chromatin remodeling, breast cancer metastasis, and drug resistance.

bioRxiv · Dec 1, 2022 · PreprintCancer Biology