Author

Maria Hernandez

Frederick National Laboratory for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. SarachakoviD· 1 shared Abir Kumar PandaiD· 1 shared Alex Rossi· 1 shared Alexander BagaeviD· 1 shared Alexandra LivanovaiD· 1 shared Amber Leila SarvestaniiD· 1 shared Andrew M. BlakelyiD· 1 shared Andrey D. Kravets· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. SarachakovORCID

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Author profile →

2 papers

Recent·Most cited

A simple circuit to sustain intact tumor microenvironments for complex drug interrogations

Amber Leila Sarvestani, Samantha M. Ruff, Kirsten Remmert, Martha E. Teke, Emily A. Verbus, Areeba Saif, Marcial Garmendia‐Cedillos, Alex Rossi, Ashley Rainey, Krystle J. Nomie, Surajit Sinha, Michael M. Wach, Carrie Ryan, Stephanie N. Gregory, Priyanka Desai, , Jonathan Matthew Hernandez

The paper develops a perfusion circuit system to preserve tumor microenvironments in 3D patient-derived tumor models for up to 48 hours, enabling complex drug interrogations.

bioRxiv · Oct 26, 2025 · PreprintCancer Biology

Long-read sequencing of single cell-derived melanoma subclones reveals divergent and parallel genomic and epigenomic evolutionary trajectories

Yuelin Liu, Anton Goretsky, Ayşe Gökçe Keşküş, Salem Malikić, Tanveer Ahmad, E. Michael Gertz, Farid Rashidi Mehrabadi, Michael C. Kelly, Maria Hernandez, Charlie Seibert, Juan Manuel Caravaca, Kayla Kline, Yongmei Zhao, Ying Wu, Biraj Shrestha, , Mikhail Kolmogorov

The paper uses long-read sequencing to analyze genomic and epigenomic changes in melanoma subclones, revealing parallel evolutionary paths and lineage-specific methylation patterns.

bioRxiv · Aug 28, 2025 · PreprintGenomics