Author

Matthew A. Campbell

New England Biolabs (United States)

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Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Bradley W. LanghorstiD· 2 shared Louise Williams· 2 shared V. K. Chaithanya PonnaluriiD· 2 shared Agata MuszyńskaiD· 1 shared Alexander BlumeiD· 1 shared Alicia AlonsoiD· 1 shared Altuna AkaliniD· 1 shared Amanda RaineiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Bradley W. LanghorstORCID

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2 papers

Recent·Most cited

EM-seq: Detection of DNA Methylation at Single Base Resolution from Picograms of DNA

Romualdas Vaisvila, V. K. Chaithanya Ponnaluri, Zhiyi Sun, Bradley W. Langhorst, Lana Saleh, Shengxi Guan, Nan Dai, Matthew A. Campbell, Brittany S. Sexton, Katherine Marks, Mala Samaranayake, James C. Samuelson, Heidi E. Church, Esta Tamanaha, Ivan Reis Correa Junior, , Theodore B. Davis

EM-seq detects DNA methylation at single base resolution using less DNA than bisulfite sequencing, showing improved accuracy and reliability.

Genome Research · Jul 1, 2021Peer-reviewedGenomics

The SEQC2 Epigenomics Quality Control (EpiQC) Study: Comprehensive Characterization of Epigenetic Methods, Reproducibility, and Quantification

Jonathan Foox, Jessica Nordlund, Claudia Lalancette, Ting Gong, Michelle R. Lacey, Samantha Lent, Bradley W. Langhorst, V. K. Chaithanya Ponnaluri, Louise Williams, Karthik Ramaswamy Padmanabhan, Raymond G. Cavalcante, Anders Lundmark, Daniel Butler, Chris Mozsary, Justin Gurvitch, , Christopher E. Mason

The paper evaluates epigenetic methods using reference materials, finding high concordance between assays and differences in performance across platforms.

bioRxiv · Dec 14, 2020 · PreprintGenomics