Author

Maxwell T. Pruner

McGovern Institute for Brain Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Heather A. SullivaniD· 2 shared Ian R. WickershamiD· 2 shared Lei JiniD· 2 shared Makoto MatsuyamaiD· 2 shared Mulangma Zhu· 2 shared Nicholas E. LeaiD· 2 shared Thomas K. LaviniD· 2 shared Yuanyuan Hou· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Heather A. SullivanORCID

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2 papers

Recent·Most cited

"Self-inactivating" rabies viruses are susceptible to loss of their intended attenuating modification

Lei Jin, Makoto Matsuyama, Heather A. Sullivan, Mulangma Zhu, Thomas K. Lavin, Yuanyuan Hou, Nicholas E. Lea, Maxwell T. Pruner, María Lucía Dam Ferdínez, Ian R. Wickersham

The paper shows that a modified rabies virus intended for noncytotoxic neuronal tracing lost its modification due to mutations, leading to paradoxical results, and that the modified virus requires exogenous protease for efficient spread.

Proceedings of the National Academy of Sciences · Feb 6, 2023Peer-reviewedNeuroscience

Long-term labeling and imaging of synaptically-connected neuronal networks in vivo using nontoxic, double-deletion-mutant rabies viruses

Lei Jin, Heather A. Sullivan, Mulangma Zhu, Thomas K. Lavin, Makoto Matsuyama, Xin Fu, Nicholas E. Lea, Ran Xu, Yuanyuan Hou, Luca Rutigliani, Maxwell T. Pruner, Kelsey R. Babcock, Jacque Pak Kan Ip, Ming Hu, Tanya L. Daigle, , Ian R. Wickersham

This paper introduces a non-toxic rabies virus system for long-term in vivo imaging of neuronal networks, showing minimal toxicity and normal visual response properties over 10 weeks.

bioRxiv · Dec 4, 2021 · PreprintNeuroscience