Author

Meghan E. Cansler

Oregon Health & Science University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

Benjamin N. BimberiD· 3 shared David Michael LewinsohniD· 3 shared Deborah A. LewinsohniD· 3 shared Dylan C. KainiD· 3 shared GW McElfreshiD· 3 shared Gwendolyn M. SwarbrickiD· 3 shared Katherine H. RottiD· 2 shared Conor McNeice· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersImmunology

Benjamin N. BimberORCID

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3 papers

Recent·Most cited

Lung Resident T Cells Across the Spectrum of TB Infection and Disease

Dylan C. Kain, GW McElfresh, Katherine H. Rott, Meghan E. Cansler, Gwendolyn M. Swarbrick, Gerhard Walzl, Nelita Du Plessis, Deborah A. Lewinsohn, Benjamin N. Bimber, David Michael Lewinsohn

This study maps human pulmonary T-cell immunity across TB infection/disease using single-cell transcriptomics and functional T-cell cloning, identifying protective immune features and a platform for TB vaccine development.

bioRxiv · Aug 17, 2026 · PreprintImmunology

Antigenic stimulation in conjunction with cytokine is required for mediating IL-17A production in human MAIT cells

Se-Jin Kim, Dylan C. Kain, Deborah A. Lewinsohn, Gwendolyn M. Swarbrick, Meghan E. Cansler, Benjamin N. Bimber, GW McElfresh, Emily Beth Wong, Sharon Khuzwayo, Thomas Riffelmacher, David Michael Lewinsohn

This study shows that IL-23 and TCR stimulation together are needed for lung MAIT cells to produce IL-17A, with distinct transcriptional changes observed.

Scientific Reports · Jul 15, 2026Peer-reviewedImmunology

Human Neonatal MR1T Cells Have Diverse TCR Usage, are Less Cytotoxic and are Unable to Respond to Many Common Childhood Pathogens.

Dylan C. Kain, Wael Awad, GW McElfresh, Meghan E. Cansler, Gwendolyn M. Swarbrick, Kean Chan Yew Poa, Conor McNeice, Gregory J. Boggy, Katherine H. Rott, Megan D. Null, David Michael Lewinsohn, Jamie Rossjohn, Benjamin N. Bimber, Deborah A. Lewinsohn

This study compares neonatal and adult MR1T cells, finding neonatal cells have diverse TCR usage, reduced cytotoxicity, and limited pathogen recognition.

bioRxiv · Mar 17, 2025 · PreprintImmunology