Author

Michael Sun

Brown UniversityPrimary ORCID profile (0000-0003-4340-8383 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Michael SuniD1 paper · University of California, Los Angeles

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adina Scheinfeld· 1 shared Aditya Dharani· 1 shared Akshada SawantiD· 1 shared Alexander S. BrodskyiD· 1 shared Andrea SchmidtiD· 1 shared Ayush BharatiiD· 1 shared Bin WuiD· 1 shared Bogdan I. FedelesiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Adina Scheinfeld

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Author profile →

2 papers

Recent·Most cited

Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM

Jorge L. Jimenez-Macias, Philippa C. Vaughn-Beaucaire, Ayush Bharati, Zheyun Xu, Megan E. Forrest, Jason S. Hong, Michael Sun, Andrea Schmidt, Jasmine Clark, William M. Hawkins, Noe B. Mercado, Jacqueline Real, Kelsey E. Huntington, Mykola I. Zdioruk, Michal Oskar Nowicki, , Sean Edward Lawler

This study identifies a 12-gene BTB signature, shows CDH5 as a core component, and demonstrates that BIA disrupts the BTB to enhance chemotherapy delivery and efficacy in GBM.

Science Advances · Feb 26, 2025Peer-reviewedCancer Biology

Autophagy Suppresses CCL2 to Preserve Appetite and Prevent Lethal Cachexia

Maria Ibrahim, Maria Gomez-Jenkins, Adina Scheinfeld, Zhengqiao Zhao, Eduardo Cararo Lopes, Akshada Sawant, Zhixian Hu, Aditya Dharani, Michael Sun, Sarah Siddiqui, Emily T. Mirek, Johan Abram-Saliba, Edmund C. Lattime, Xiaoyang Su, Tobias Janowitz, , Eileen White

This paper shows autophagy prevents cachexia by suppressing CCL2, which damages appetite-promoting neurons, leading to lethal weight loss in mice.

bioRxiv · Feb 20, 2025 · PreprintMolecular Biology