Author

William M. Hawkins

Brown University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Noe B. MercadoiD· 2 shared Philippa C. Vaughn-BeaucaireiD· 2 shared Sean Edward LawleriD· 2 shared Alexander S. BrodskyiD· 1 shared Andrea Schmidt· 1 shared Andrea SchmidtiD· 1 shared Austin Jacobson· 1 shared Ayaan Akhtar· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Noe B. MercadoORCID

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2 papers

Recent·Most cited

Preclinical evaluation of Brincidofovir in glioblastoma demonstrates improved long term-survival and cytomegalovirus-dependent and independent effects

Noe B. Mercado, Philippa C. Vaughn-Beaucaire, William M. Hawkins, Andrea Schmidt, Jasmine S. Clark, Michelle Shub, Mariia Vorobeva, Yovany Padilla, Austin Jacobson, Ayaan Akhtar, Paola Sundaram, Eleni Panagioti, Eain A. Murphy, James Arthur Lederer, Masatoshi Hazama, , Sean Edward Lawler

This study evaluates Brincidofovir's effects on glioblastoma, showing improved survival and both CMV-dependent and independent antitumor activity.

bioRxiv · Aug 21, 2026 · PreprintCancer Biology

Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM

Jorge L. Jimenez-Macias, Philippa C. Vaughn-Beaucaire, Ayush Bharati, Zheyun Xu, Megan E. Forrest, Jason S. Hong, Michael Sun, Andrea Schmidt, Jasmine Clark, William M. Hawkins, Noe B. Mercado, Jacqueline Real, Kelsey E. Huntington, Mykola I. Zdioruk, Michal Oskar Nowicki, , Sean Edward Lawler

This study identifies a 12-gene BTB signature, shows CDH5 as a core component, and demonstrates that BIA disrupts the BTB to enhance chemotherapy delivery and efficacy in GBM.

Science Advances · Feb 26, 2025Peer-reviewedCancer Biology