Author

Miechaleen D. Diers

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Beau R. WebberiD· 2 shared Branden S. MoriarityiD· 2 shared Cara-lin LonetreeiD· 2 shared Mitchell G. KluesneriD· 2 shared Nicholas J. SlipekiD· 2 shared Walker S. LahriD· 2 shared Alexandria K. Gilkey· 1 shared Amber N. McElroyiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBioengineering

Beau R. WebberORCID

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Author profile →

2 papers

Recent·Most cited

A Singular Base Editing Platform for Polyfunctional Multiplex Engineering of Immune Cells

Joseph G. Skeate, Nicholas J. Slipek, Walker S. Lahr, Shambojit Roy, Bryce J. Wick, Bibekananda Kar, Jae-Woong Chang, Erin M. Stelljes, Alexandria K. Gilkey, Prateek P. Thenge, Miechaleen D. Diers, Joshua B. Krueger, Ethan M. Niemeyer, Cara-lin Lonetree, Mitchell G. Kluesner, , Beau R. Webber

This paper develops a base editing platform to efficiently and safely engineer CAR T cells with multiple gene knockouts and insertions.

Molecular Therapy · Jul 18, 2026Peer-reviewedBioengineering

Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors

Beau R. Webber, Cara-lin Lonetree, Mitchell G. Kluesner, Matthew J. Johnson, Emily J. Pomeroy, Miechaleen D. Diers, Walker S. Lahr, Garrett M. Draper, Nicholas J. Slipek, Branden A. Smeester, Klaus N. Lovendahl, Amber N. McElroy, Wendy Ryan Gordon, Mark J. Osborn, Branden S. Moriarity

This study develops a method to efficiently edit multiple genes in human T cells using base editors, reducing off-target effects and improving safety for immunotherapy.

Nature Communications · Nov 19, 2019Peer-reviewedGenetics