Author

Cheng Sun

University of Science and Technology of ChinaORCID 0000-0002-8799-7426Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Cheng Sun3 papers · Sheng Jing Hospital

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Andrew M. KropinskiiD· 1 shared Armand Kurum· 1 shared Bing Feng· 1 shared Björn NashaniD· 1 shared Chao Huang· 1 shared Chengming ZhuiD· 1 shared Fangyi WangiD· 1 shared Guoxin CaiiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBioinformatics

Andrew M. KropinskiORCID

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3 papers

Recent·Most cited

Metabolic reinvigoration of NK cells by IL-21 enhances immunotherapy against MHC-I deficient solid tumors

Yi Wang, Chao Huang, Guoxin Cai, Massimo Andreatta, Armand Kurum, Yang Zhao, Bing Feng, Min Gao, Santiago J. Carmona, Zhan Zhou, Cheng Sun, Yugang Guo, Li Tang

This paper shows that IL-21-Fc reprograms NK cell metabolism to enhance their function against MHC-I deficient tumors, leading to tumor eradication in preclinical models.

Cell Reports · Feb 26, 2026Peer-reviewedCancer Biology

Systematic characterization of chromodomain proteins revealsan H3K9me1/2 reader regulating aging in C. elegans

Xinhao Hou, Mingjing Xu, Chengming Zhu, Jianing Gao, Meili Li, Xiangyang Chen, Cheng Sun, Björn Nashan, Jianye Zang, Ying Zhou, Shouhong Guang, Xuezhu Feng

The paper systematically characterizes chromodomain proteins in C. elegans, identifying CEC-5 as an H3K9me1/2 reader that regulates aging through interactions with MET-2.

Nature Communications · Mar 6, 2023Peer-reviewedMolecular Biology

Mining bacterial NGS data vastly expands the complete genomes of temperate phages

Xianglilan Zhang, Ruohan Wang, Xiangcheng Xie, Yunjia Hu, Jianping Wang, Qiang Sun, Xikang Feng, Wei Lin, Shanwei Tong, Wei Yan, Huiqi Wen, Mengyao Wang, Shixiang Zhai, Cheng Sun, Fangyi Wang, , Yigang Tong

This study expands the number of complete temperate phage genomes by over 100-fold using a novel computational method applied to bacterial NGS data.

NAR Genomics and Bioinformatics · Jul 9, 2022Peer-reviewedBioinformatics