Author

Modestas Matusevicius

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Assay:protein sequence· 1

Frequent Co-Authors

Sundeep Chaitanya VedithiiD· 2 shared Tom L. BlundelliD· 2 shared Ali F. AlsulamiiD· 1 shared Anastasiia GusachiD· 1 shared Asma MuniriD· 1 shared Christopher A. BeaudoiniD· 1 shared Christopher G. TateiD· 1 shared Dimitri Y. ChirgadzeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Sundeep Chaitanya VedithiORCID

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Author profile →

2 papers

Recent·Most cited

HANSEN: An Integrated Structural and Functional Proteome Resource for Structure-Guided Drug Discovery in Mycobacterium leprae

Sundeep Chaitanya Vedithi, Rebecca Rees, Sony Malhotra, Asma Munir, Modestas Matusevicius, Ali F. Alsulami, Christopher A. Beaudoin, Kiran Sai Sunkara, Madhusmita Das, Tom L. Blundell, Rodrigo Andres Floto

Web resource offering predicted monomeric and oligomeric structures for 1,603 M. leprae proteins, with pockets, epitope scores, essentiality and a target priority ranking, plus a nanopore resistance-calling module.

bioRxiv · Aug 29, 2026 · PreprintBioinformatics✦ In-depth digest

Insights from aquaporin structures into drug-resistant sleeping sickness

Modestas Matusevicius, Robin Adam Corey, Marcos Gragera, Keitaro Yamashita, Teresa Sprenger, Marzuq A. Ungogo, James N. Blaza, Pablo Castro‐Hartmann, Dimitri Y. Chirgadze, Sundeep Chaitanya Vedithi, Pavel Afanasyev, Roberto Melero, Rangana Warshamanage, Anastasiia Gusach, J.M. Carazo, , Simone N. Weyand

This study determines the structure of TbAQP2 bound to drugs and glycerol, revealing how mutations in the channel lead to drug resistance in Trypanosoma brucei.

eLife · Dec 31, 2025Peer-reviewedMolecular Biology