Author

Mohammed Tarek Islam

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Daniel Medina-CanoiD· 3 shared Thomas VierbucheniD· 3 shared Sanjana Dixit· 2 shared Yuan LiniD· 2 shared Alissa J. TrzeciakiD· 1 shared Ann K BaakoiD· 1 shared C. Stephanie· 1 shared Emily K. Corrigan· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersDevelopmental Biology

Daniel Medina-CanoORCID

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4 papers

Recent·Most cited

A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro

Daniel Medina-Cano, Mohammed Tarek Islam, Veronika Petrova, Sanjana Dixit, Zerina Balic, Marty G. Yang, Matthias Stadtfeld, Emily S. W. Wong, Thomas Vierbuchen

The paper develops a mouse cortical organoid platform to study cis-regulatory evolution and identifies genes with dynamic allelic imbalances during neurogenesis.

Developmental Cell · Aug 27, 2025Peer-reviewedDevelopmental Biology

Modeling tissue-resident macrophage development from mouse pluripotent stem cells

Ann K Baako, Ragavi Vijayakumar, Daniel Medina-Cano, Zhaoquan Wang, Jesús E. Romero-Pichardo, Kelvin Fadojutimi, C. Stephanie, Yuan Lin, Mohammed Tarek Islam, Sanjana Dixit, Alissa J. Trzeciak, Justin S. A. Perry, Thomas Vierbuchen

This paper develops a protocol to efficiently generate tissue-resident macrophages from mouse pluripotent stem cells, enabling in vitro and in vivo modeling of their development.

bioRxiv · May 1, 2025 · PreprintDevelopmental Biology

Rapid and robust directed differentiation of mouse epiblast stem cells into definitive endoderm and forebrain organoids

Daniel Medina-Cano, Emily K. Corrigan, Rachel A. Glenn, Mohammed Tarek Islam, Yuan Lin, Juliet Kim, Hyunwoo Cho, Thomas Vierbuchen

The paper presents optimized protocols for generating definitive endoderm and forebrain-patterned neural organoids from mouse epiblast stem cells.

Development · Jul 28, 2022Peer-reviewedDevelopmental Biology

Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure

Eric Brooks, Mohammed Tarek Islam, Kathryn V. Anderson, Jennifer A. Zallen

This study identifies Sonic hedgehog signaling as a regulator of patterned apical constriction during cranial neural tube closure, revealing its role in preventing exencephaly.

eLife · Oct 26, 2020Peer-reviewedDevelopmental Biology