Author

Morgan C. Pait

Wake Forest University Health Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:non-human primate· 1

Frequent Co-Authors

Shannon L. MacauleyiD· 3 shared Caitlin M. CarrolliD· 2 shared James Andy Snipes· 2 shared Sarah D. KayeiD· 2 shared Ashish KumariD· 1 shared Celeste M M. KarchiD· 1 shared Christopher B. NewgardiD· 1 shared Colin G. NicholsiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Shannon L. MacauleyORCID

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3 papers

Recent·Most cited

Novel method for collecting hippocampal interstitial fluid extracellular vesicles (EV-ISF) reveals sex-dependent changes in microglial EV proteome in response to Aβ pathology

Morgan C. Pait, Sarah D. Kaye, Yixin Su, Ashish Kumar, Sangeeta Singh, Stephen C. Gironda, Samantha Vincent, Maria Anwar, Caitlin M. Carroll, James Andy Snipes, Jingyun Lee, Cristina M. Furdui, Gagan Deep, Shannon L. Macauley

The paper develops a method to collect hippocampal interstitial fluid extracellular vesicles (EVISF) and finds sex-dependent changes in microglial EV proteome related to Aβ pathology.

Journal of Extracellular Vesicles · Jan 1, 2024Peer-reviewedNeuroscience

Kir6.2-containing KATP channels are necessary for glucose dependent increases in amyloid-beta and Alzheimer's-related pathology

John Grizzanti, William R. Moritz, Morgan C. Pait, Molly Stanley, Sarah D. Kaye, Caitlin M. Carroll, Nicholas J. Constantino, Lily J. Deitelzweig, Noelle Isabella Nicol, James Andy Snipes, Derek Kellar, Emily E. Caesar, Jasmeen Dhillon, Maria Sara Remedi, Celeste M M. Karch, , Shannon L. Macauley

This study shows that Kir6.2-KATP channels are necessary for hyperglycemia-induced increases in amyloid-beta and Alzheimer's pathology by regulating lactate transport and Aβ release.

bioRxiv · Feb 20, 2022 · PreprintNeuroscience

Type-2-diabetes alters CSF but not plasma metabolomic and AD risk profiles in vervet monkeys

Kylie Kavanagh, Stephen M. Day, Morgan C. Pait, William R. Mortiz, Christopher B. Newgard, Olga Ilkayeva, Donald A. McClain, Shannon L. Macauley

This study shows that type 2 diabetes in vervet monkeys alters cerebrospinal fluid metabolites and amyloid levels, but not plasma metabolites or AD risk profiles.

Frontiers in Neuroscience · Aug 28, 2019Peer-reviewedNeuroscience