Author

N. Shimizu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:imaging· 2 Research Focus:protein folding & dynamics· 2 Organism:zebrafish· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. Inoue· 2 shared A. MarteliD· 1 shared E. Oya· 1 shared H. Furuie· 1 shared H. Iwase· 1 shared H. Miyahara· 1 shared H. Shiraishi· 1 shared J. Nogami· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersCell Biology

M. Inoue

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Intradermal Administration of Rescue Dose of Antiemetics in Chemotherapy-induced Nausea and Vomiting

M. Maekawa-Matsuura, N. Shimizu, Y. Sakamaki, E. Oya, S. Shimizu, Y. Iwase

The paper compares the pharmacokinetics of subcutaneous and intradermal antiemetic administration in rats to evaluate their effectiveness for rapid, self-administered rescue therapy for chemotherapy-induced nausea and vomiting.

bioRxiv · Sep 27, 2023 · PreprintPharmacology & Toxicology

Biallelic variants in LARS1 induce steatosis in developing zebrafish liver via enhanced autophagy

M. Inoue, W. A. Sebastian, S. Sonoda, H. Miyahara, N. Shimizu, H. Shiraishi, M. Maeda, K. Yanagi, T. Kaname, R. Hanada, T. Hanada, K. Ihara

This study identifies biallelic LARS1 variants as a cause of infantile liver failure by showing they induce steatosis via enhanced autophagy in zebrafish.

bioRxiv · Sep 21, 2023 · PreprintCell Biology

Structure of full-length ERGIC-53 in complex with MCFD2 for cargo transport

S. Watanabe, Y. Kise, K. Yonezawa, M. Inoue, N. Shimizu, O. Nureki, K. Inaba

This study determines the cryo-EM structure of full-length ERGIC-53 complexed with MCFD2, revealing its tetrameric architecture and mechanism of cargo transport.

bioRxiv · Aug 27, 2023Biochemistry

Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning

Y. Akieda, S. Ogamino, H. Furuie, S. Ishitani, R. Akiyoshi, J. Nogami, T. Masuda, N. Shimizu, Y. Ohkawa, T. Ishitani

The paper shows that cell competition corrects noisy Wnt/β-catenin gradients by eliminating unfit cells, ensuring robust embryonic patterning.

bioRxiv · Sep 25, 2018Cell Biology

Direct Evidence of Effect of Glycerol on Hydration and Helix-to-Sheet Transition of Myoglobin

M. Hirai, S. Ajito, M. Sugiyama, H. Iwase, S.-I. Takata, N. Shimizu, N. Igarashi, A. Martel, L. Porcar

This paper investigates glycerol's effect on myoglobin's hydration and structural transitions using scattering techniques, showing preservation of hydration shells at low concentrations and structural stabilization at higher concentrations.

bioRxiv · Mar 8, 2018 · PreprintBiophysics