Author

Niki Sepanj

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra SilvaiD· 1 shared Ana Luı́sa CarvalhoiD· 1 shared Andreia Neves‐CarvalhoiD· 1 shared Andreia Teixeira‐CastroiD· 1 shared Annalisa PastoreiD· 1 shared Beatriz Rocha Ilidio RodriguesiD· 1 shared Carter LantziD· 1 shared Daniela Monteiro‐FernandesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Alexandra SilvaORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies

Alexandra Silva, Sara Duarte‐Silva, Pedro Miguel Martins, Beatriz Rocha Ilidio Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Pérez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana S. Fraga, James W. Noble, Carter Lantz, , Sandra Macedo‐Ribeiro

This study shows that CLR01, a supramolecular tweezer, reduces Atx3 aggregation by binding to a specific site, delaying fibril formation and improving symptoms in SCA3 models.

Advanced Science · Nov 26, 2025Peer-reviewedBiophysics