Author

Julio Vieyto‐Nuñez

TU Dortmund UniversityORCID 0000-0002-3128-6764Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Elsa Sánchez‐GarcíaiD· 3 shared Joel Mieres‐PéreziD· 2 shared Yasser Almeida‐HernándeziD· 2 shared Alexandra SilvaiD· 1 shared Ana Luı́sa CarvalhoiD· 1 shared Andreia Neves‐CarvalhoiD· 1 shared Andreia Teixeira‐CastroiD· 1 shared Andy ChevignéiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersBiophysics

Elsa Sánchez‐GarcíaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies

Alexandra Silva, Sara Duarte‐Silva, Pedro Miguel Martins, Beatriz Rocha Ilidio Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Pérez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana S. Fraga, James W. Noble, Carter Lantz, , Sandra Macedo‐Ribeiro

This study shows that CLR01, a supramolecular tweezer, reduces Atx3 aggregation by binding to a specific site, delaying fibril formation and improving symptoms in SCA3 models.

Advanced Science · Nov 26, 2025Peer-reviewedBiophysics

MTBP allosterically activates Cdk8-CycC kinase activity

Eman Zaffar, Julio Vieyto‐Nuñez, Katerina Pravi, Mohammed Faidh Aslam, Yasser Almeida‐Hernández, Joel Mieres‐Pérez, Farnusch Kaschani, Markus Kaiser, Anika Kroesen, Dominik Boos, Elsa Sánchez‐García

The paper shows that MTBP allosterically activates Cdk8-CycC kinase activity through distinct mechanisms from Med12, enabling substrate-specific phosphorylation and impacting cancer biology.

bioRxiv · Jun 16, 2025 · PreprintBiochemistry

GPR15LG binds CXCR4 and synergistically modulates CXCL12-induced cell signaling and migration

Dan Albers, Sofya Novikova, Julio Vieyto‐Nuñez, Yasser Almeida‐Hernández, Chiara Pastorio, Florian Klassen, Dana Weiss, Pascal von Maltitz, Janeni Jaikishan, Moumita Datta, Hassan Jumaa, Billy Michael Chelliah Jebaraj, Stephan Stilgenbauer, Manish Kumar, Palash Chandra Maity, , Mirja Harms

This study shows GPR15LG binds CXCR4, enhancing CXCL12-induced signaling and promoting cell migration in immune and cancer cells.

Cell Communication and Signaling · May 20, 2025Peer-reviewedCell Biology