Author

Noor Radde

The University of Texas at Austin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Adam Samuel SperlingiD· 1 shared Andi Cheng· 1 shared Angelique Pham· 1 shared César de la Fuente‐NúñeziD· 1 shared Christina DeBarro· 1 shared Dennis M. MishleriD· 1 shared Ditsa SarkariD· 1 shared Diya BhatiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperSynthetic Biology

Adam Samuel SperlingORCID

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Author profile →

3 papers

Recent·Most cited

A Lenalidomide-Inducible Suicide Switch for Gene- and Cell-Based Therapy

Ditsa Sarkar, William Lin, Nelson H. Knudsen, Jalen Evans, Joanna Kim, Stephen M. Coscia, Isabel C. Lane, Andi Cheng, Noor Radde, Manuella Talla Takoukam, Angelique Pham, Tamina Kienka, Emily Schneider, Gabriele Jessica Kembuan, Mikolaj Michal Slabicki, , Max Jan

This paper introduces a lenalidomide-inducible suicide switch for gene- and cell-based therapies that enables safe and effective cell depletion without detectable leakiness.

bioRxiv · Oct 1, 2026 · PreprintSynthetic Biology

Defining the importance of the arginine loop region of protegrin-1 for antimicrobial activity towards colistin-resistant Klebsiella pneumoniae.

Christina DeBarro, Sofia Assent, Hannah Makhecha, Noor Radde, Rakesh Krishnan, Justin R. Randall, César de la Fuente‐Núñez, Renee M. Fleeman

The paper investigates how mutations in protegrin-1 affect its antimicrobial activity against colistin-resistant Klebsiella pneumoniae, finding structural changes have a greater impact than charge reduction.

bioRxiv · May 28, 2025 · PreprintMicrobiology

Measuring the burden of hundreds of BioBricks defines an evolutionary limit on constructability in synthetic biology

Noor Radde, Genevieve A. Mortensen, Diya Bhat, Shireen Shah, Joseph J. Clements, Sean P. Leonard, Matthew J. McGuffie, Dennis M. Mishler, Jeffrey E. Barrick

The paper measures the growth burden of 301 BioBricks in E. coli and finds that 19.6% reduce growth, with most burdens explained by gene expression resource diversion.

Nature Communications · Jul 24, 2024Peer-reviewedSynthetic Biology