Long-read proteogenomic atlas of human neuronal differentiation reveals isoform diversity informing neurodevelopmental risk mechanisms
Nuo Xu, Katherine M Rynard, Elizabeth Radley, Ai Tian, Maahil Arshad, Chaoying Long, Jimmy Ly, Hua Luo, Ellie Hogan, Maria Eleni Fafouti, Melanie Davie, Fatima Naimi, Yun Li, John A. Calarco, Brett Trost, , Shreejoy J. Tripathy
The paper generates a high-resolution proteogenomic atlas of human neuronal development using long-read RNA sequencing and proteomics, revealing novel isoforms and their role in neurodevelopmental risk mechanisms.
Nature Communications · Aug 19, 2026Peer-reviewedBioinformatics