P. Chakrabarti

Inhibition of Extracellular Vesicle-Associated MMP2 Abrogates Intercellular Transfer of Hepatic miR-122 to Tissue Macrophages and Curtails Liver Inflammation

The paper shows that inhibiting MMP2 on extracellular vesicles reduces miR-122 transfer to macrophages, thereby decreasing liver inflammation.

Lipid Droplets Promote Phase Separation of Ago2 to Accelerate Dicer1 Loss and Decelerate miRNA Activity in Lipid Exposed Hepatic Cells

The paper shows lipid droplets promote Ago2 phase separation, reduce Dicer1 levels, and decrease miR-122 activity in hepatic cells under lipotoxic stress.

Resveratrol prevents amyloid fibrillation of insulin by arresting it in a bioactive oligomeric form

This study shows resveratrol prevents insulin fibrillation by keeping it in a bioactive oligomeric form and retains its biological activity without toxicity.