Author

N. Karagianni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Immunology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:ATAC-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

G. KOLLIAS· 4 shared E. CHRISTODOULOU-VAFEIADOU· 3 shared L. NTARI· 3 shared C. GEKA· 2 shared C. Tzaferis· 2 shared D. Papadopoulou· 2 shared F. Roumelioti· 2 shared M. Armaka· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

G. KOLLIAS

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Novel human IL-23A Overexpressing Mouse Model of Systemic Lupus Erythematosus

E. CHRISTODOULOU-VAFEIADOU, C. GEKA, L. ILIOPOULOU, L. NTARI, M. C. DENIS, N. KARAGIANNI, G. KOLLIAS

This paper creates a human IL-23A overexpressing mouse model of SLE and shows it develops autoimmune features similar to human SLE.

bioRxiv · Nov 8, 2023Immunology

Repurposing of Amisulpride, a known antipsychotic drug, to target synovial fibroblasts activation in arthritis.

D. Papadopoulou, F. Roumelioti, C. Tzaferis, P. Chouvardas, A.-K. Pedersen, F. Charalampous, E. Christodoulou-Vafeiadou, L. Ntari, N. Karagianni, M. Denis, J. V. Olsen, A. N. Matralis, G. Kollias

This study identifies Amisulpride as a potential therapeutic for arthritis by reducing synovial fibroblast activation, independent of its known targets.

bioRxiv · Aug 2, 2022 · PreprintPharmacology & Toxicology

miR-221/222 drive synovial fibroblast expansion and pathogenesis of TNF-mediated arthritis

F. Roumelioti, C. Tzaferis, D. Konstantopoulos, D. Papadopoulou, A. Prados, M. Sakkou, A. Liakos, P. Chouvardas, T. Meletakos, Y. Pandis, N. Karagianni, M. Denis, M. Fousteri, M. Armaka, G. Kollias

This study shows miR-221/222 promotes synovial fibroblast expansion and worsens TNF-mediated arthritis by regulating cell cycle and ECM pathways.

bioRxiv · Jul 22, 2022 · PreprintCell Biology

Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis

E. Christodoulou-Vafeiadou, C. Geka, L. Ntari, K. Kranidioti, E. Argyropoulou, F. Meier, M. Armaka, I. Mourouzis, C. Pantos, M. Rouchota, G. Loudos, M. C. Denis, N. Karagianni, G. Kollias

This paper characterizes a transmembrane TNF-driven mouse model of spondyloarthritis, showing ectopic bone formation, systemic bone loss, and comorbid heart valve pathology, with early anti-TNF treatment reducing inflammation.

bioRxiv · May 14, 2020Pathology