Author

P. Kaleebu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:metagenomics· 2 Approach:statistical model· 2

Frequent Co-Authors

H. Brown· 2 shared J. Fox· 2 shared J. Frater· 2 shared M. Pace· 2 shared N. Robinson· 2 shared P. Klenerman· 2 shared S. Fidler· 2 shared A. A. Sharma· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

H. Brown

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Author profile →

5 papers

Recent·Most cited

Ticks; a reservoir for virus emergence at the human-livestock interface in Uganda

S. A. Atim, S. Ashraf, M. Niebel, A. Ssekagiri, M. N. Hardy, J. G. Shepherd, L. Tong, A. R. Ademun, P. Vudriko, J. Erume, S. Odongo, D. Muhanguzi, W. Nguma, T. Nakayiki, J. Namulondo, , E. C. Thomson

The paper sequences ticks in Uganda to identify viruses, finding 22 species including 8 pathogens and 5 novel viruses, with orthonairoviruses being prevalent.

bioRxiv · Mar 10, 2023 · PreprintMicrobiology

Impaired HIV-specific T-cell responses in HIV and S. mansoni coinfected Ugandans.

A. E. Obuku, A. A. Sharma, A. Rukundo, M. Odong, B. Auma, J. S. Serwanga, R. Nkangi, Z. Nakitto, M. Joloba, G. Pantaleo, P. Kaleebu, R. P. Sekaly

The paper examines how S. mansoni infection impacts HIV-specific T-cell responses in coinfected Ugandan fishermen, finding reduced immune responses after parasite clearance.

bioRxiv · Nov 1, 2022 · PreprintImmunology

Bacterial Microbiome and Host Inflammatory Gene Expression in Foreskin Tissue

B. S. Maust, S. Petkov, C. Herrera, C. Feng, B. P. Brown, L. Lebina, D. Opoka, A. Ssemata, N. Pillay, J. Serwanga, P. Seatlholo, P. Namubiru, G. Odoch, S. Mugaba, T. Seiphetlo, , the CHAPS team

The paper analyzes the foreskin microbiome and host gene expression in adolescents from South Africa and Uganda, finding no treatment effect on bacterial communities but inverse correlations between bacterial abundance and inflammatory gene expression.

bioRxiv · Aug 29, 2022Microbiology

Expression of type I interferon-associated genes at antiretroviral therapy interruption predicts HIV virological rebound

P. Zacharopoulou, E. Marchi, A. Ogbe, N. Robinson, H. Brown, M. Jones, L. Parolini, M. Pace, N. Grayson, P. Kaleebu, H. Rees, S. Fidler, P. Goulder, P. Klenerman, J. Frater

The paper identifies type I interferon-associated gene expression in CD4 T cells as a predictor of delayed HIV viral rebound after antiretroviral therapy interruption.

bioRxiv · Nov 24, 2020 · PreprintMicrobiology

Enrichment of the HIV reservoir in CD32+ CD4 T cells occurs early in blood and tissue

G. Martin, M. Pace, J. Thornhill, C. Phetsouphanh, J. Meyerowitz, M. Gossez, E. Hopkins, H. Brown, N. Robinson, N. Olejniczak, G. Ramjee, P. Kaleebu, K. Porter, C. Willberg, P. Klenerman, , J. Frater

The paper shows HIV DNA enrichment in CD32+ CD4 T cells early in infection but finds no correlation with rebound viraemia or HIV DNA levels.

bioRxiv · Jul 27, 2017Immunology