Author

T. Beck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Assay:imaging· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

J. Guck· 4 shared K. Kim· 3 shared S. Alberti· 3 shared A. Keniry· 2 shared A. V. Taubenberger· 2 shared C. Moeckel· 2 shared K. Breslin· 2 shared M. E. Blewitt· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersBiophysics

J. Guck

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Optical characterization of molecular interaction strength in protein condensates

T. Beck, L.-M. van der Linden, W. M. Borcherds, K. Kim, R. Schluessler, P. Mueller, T. Franzmann, C. Moeckel, R. Goswami, M. Leaver, T. Mittag, S. Alberti, J. Guck

The paper introduces optical techniques to measure molecular interaction strength and physical properties of protein condensates, showing how sequence variations and environmental factors affect these properties.

bioRxiv · Mar 19, 2024Biophysics

Estimation of the mass density of biological matter from refractive index measurements

C. Moeckel, T. Beck, S. Kaliman, S. Abuhattum, K. Kim, J. Kolb, D. Wehner, V. Zaburdaev, J. Guck

This paper estimates mass density from refractive index measurements using a method that incorporates biochemical composition assumptions and uncertainty analysis, validated on biological samples.

bioRxiv · Dec 5, 2023Biophysics

Predominant myosin super-relaxed state in canine myocardium with naturally occurring dilated cardiomyopathy

J. Ochala, C. T. A. Lewis, T. Beck, H. Iwamoto, A. Hessel, K. Campbell, G. Pyle

This study finds that myosin in DCM-affected dogs has increased super-relaxed state and is rescued by EMD-57033.

bioRxiv · Mar 10, 2023Pathology

A method for stabilising the XX karyotype in female mESC cultures

A. Keniry, N. Jansz, P. F. Hickey, K. Breslin, M. Iminitoff, T. Beck, M. E. Ritchie, M. E. Blewitt

This paper describes a method to maintain XX karyotype in female mESCs, preventing their transition to XO and preserving female-specific pluripotency.

bioRxiv · Apr 7, 2022Cell Biology

Mapping tumor spheroid mechanics in dependence of 3D microenvironment stiffness and degradability by Brillouin microscopy

V. Mahajan, T. Beck, P. Gregorczyk, A. Ruland, S. Alberti, J. Guck, C. Werner, R. Schluessler, A. V. Taubenberger

This study uses Brillouin microscopy to map tumor spheroid mechanics in 3D hydrogels, showing that stiffness and degradability affect mechanical properties and cell invasion.

bioRxiv · Oct 12, 2021Biophysics

Correlative all-optical quantification of mass density and mechanics of sub-cellular compartments with fluorescence specificity

R. Schlüssler, K. Kim, M. Nötzel, A. V. Taubenberger, S. Abuhattum, T. Beck, P. Müller, S. Maharana, G. Cojoc, S. Girardo, A. Hermann, S. Alberti, J. Guck

This paper introduces FOB microscopy to measure sub-cellular density and mechanics with fluorescence specificity, revealing differences between nucleoplasm and cytoplasm.

bioRxiv · Oct 30, 2020Biophysics

Xmas ESC: A new female embryonic stem cell system that reveals the BAF complex as a key regulator of the establishment of X chromosome inactivation

A. Keniry, N. Jansz, L. J. Gearing, I. Wanigasuriya, J. Chen, C. M. Nefzger, P. F. Hickey, Q. Gouil, J. Liu, K. Breslin, M. Iminitoff, T. Beck, A. Tapia del Fierro, S. A. Kinkel, P. C. Taberlay, , M. E. Blewitt

The paper introduces a female ESC system called Xmas that identifies the BAF complex as essential for X chromosome inactivation.

bioRxiv · Sep 13, 2019 · PreprintCell Biology