Author

P. Pescher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

G. F. Spaeth· 3 shared B. Vojtkova· 2 shared G. Bussotti· 2 shared J. Sadlova· 2 shared P. Volf· 2 shared A. Boland· 1 shared B. Li· 1 shared C. Besse· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersEvolutionary Biology

G. F. Spaeth

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage

G. Bussotti, B. Li, P. Pescher, B. Vojtkova, I. Louradour, K. Pruzinova, J. Sadlova, P. Volf, G. F. Spaeth

This study identifies oxidative DNA damage signatures in Leishmania donovani during sand fly infection, linking them to allelic and haplotype selection through genomic analysis.

bioRxiv · May 2, 2022Evolutionary Biology

Experimental evolution reveals post-transcriptional regulation as a novel driver of Leishmania fitness gain

L. Piel, K. S. Rajan, G. Bussotti, H. Varet, R. Legendre, C. Proux, T. Douche, Q. Giai Gianetto, T. Chaze, T. Cokelaer, B. Vojtkova, N. Gordon-Bar, T. Doniger, S. Cohen-Chalamish, P. Rengaraj, , G. F. Spaeth

This study shows that post-transcriptional regulation, not just genome instability, drives fitness gain in Leishmania parasites during in vitro adaptation.

bioRxiv · Mar 22, 2021 · PreprintMicrobiology

Dynamic High-Content Imaging Reveals Surface Exposure Of Virulent Leishmania Amastigotes In Infected Macrophages Undergoing Pyroptosis

T. Rosazza, H. Lecoeur, T. Blisnick, M. Moya-Nilges, P. Pescher, P. Bastin, E. Prina, G. F. Spaeth

This study shows that Leishmania-infected macrophages undergo pyroptosis, exposing amastigotes to the extracellular environment, which may aid parasite spread.

bioRxiv · Feb 3, 2020Immunology