Author

P. R. Johnson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

L. Piemonti· 2 shared A. Boufersaoui· 1 shared A. Clark· 1 shared A. H. Shilleh· 1 shared A. M. J. Shapiro· 1 shared A. Martinez-sanchez· 1 shared A. P. Davies· 1 shared B. HASTOY· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

L. Piemonti

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

High-resolution glucose tracing and in situ imaging reveals regulated lactate production in human pancreatic β cells

F. Cuozzo, K. Viloria, A. H. Shilleh, D. Nasteska, C. Frazer-Morris, Z. Jiao, A. Boufersaoui, B. Marzullo, H. R. Smith, C. Bonner, J. Kerr-Conte, F. Pattou, R. Nano, L. Piemonti, P. R. Johnson, , D. J. Hodson

The paper uses metabolic tracing and imaging to show that human pancreatic β cells produce lactate, regulated by LDHB expression, which affects Ca2+ spiking without altering ATP/ADP levels.

bioRxiv · Dec 21, 2022 · PreprintPhysiology

Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell identity and function.

L. Lopez-Noriega, R. M. Callingham, A. Martinez-sanchez, S. Nawaz, G. Pizza, N. Haberman, N. Cvetesic, M.-S. Nguyen-Tu, B. Lenhard, P. Marchetti, L. Piemonti, E. J. P. de Koning, A. M. J. Shapiro, P. R. Johnson, I. Leclerc, , G. A. Rutter

This study investigates the role of Pax6os1/PAX6-AS1 in beta cell identity and function, finding that its upregulation in diabetes contributes to impaired functionality and that targeting it may improve glucose homeostasis.

bioRxiv · Jul 17, 2020 · PreprintCell Biology