Author

R. Nano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

L. Piemonti· 2 shared A. A. Chetta· 1 shared A. Assanelli· 1 shared A. Boufersaoui· 1 shared A. C. Vertegaal· 1 shared A. Campos Caro· 1 shared A. Clark· 1 shared A. Dorronsoro· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

L. Piemonti

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LRH-1/NR5A2 Activation Rewires Immunometabolism Blunting Inflammatory Immune Cell Progression in Individuals with Type 1 Diabetes and Enhances Human Islet Function in Mice

N. Cobo-vuilleumier, S. Rodriguez-Fernandez, L. Lopez-Noriega, P. I. Lorenzo, J. M. Franco, c. C. Lachaud, E. Martin-Vazquez, R. Araujo Legido, A. Dorronsoro, R. Lopez-Fernandez-Sobrino, b. Fernandez-santos, D. Salas-Lloret, N. van Overbeek, M. Ramos-Rodriguez, C. Mateo-Rodriguez, , B. R. Gauthier

This study shows that activating LRH-1/NR5A2 reduces inflammation in T1D by altering immune cell metabolism and improves human islet function in mice.

bioRxiv · Sep 18, 2023 · PreprintCell Biology

High-resolution glucose tracing and in situ imaging reveals regulated lactate production in human pancreatic β cells

F. Cuozzo, K. Viloria, A. H. Shilleh, D. Nasteska, C. Frazer-Morris, Z. Jiao, A. Boufersaoui, B. Marzullo, H. R. Smith, C. Bonner, J. Kerr-Conte, F. Pattou, R. Nano, L. Piemonti, P. R. Johnson, , D. J. Hodson

The paper uses metabolic tracing and imaging to show that human pancreatic β cells produce lactate, regulated by LDHB expression, which affects Ca2+ spiking without altering ATP/ADP levels.

bioRxiv · Dec 21, 2022 · PreprintPhysiology

Follicular helper T cell signature of replicative exhaustion, apoptosis and senescence in common variable immunodeficiency

G. Milardi, B. Di Lorenzo, J. Gerosa, F. Barzaghi, G. Di Matteo, M. Omrani, T. Jofra, I. Merelli, M. Barcella, F. Ferrua, F. P. Giuffrida, F. Dionisio, P. Rovere-Querini, S. Marktel, A. Assanelli, , C. Cancrini

The paper identifies a subset of CVID patients with Tfh cells showing replicative exhaustion, apoptosis, and senescence linked to DNA repair and telomere elongation defects.

bioRxiv · Jun 15, 2021Immunology