Author

Pierfrancesco Vargiu

Spanish National Cancer Research Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Sagrario OrtegaiD· 2 shared Aina BernaliD· 1 shared Ana Cayuela· 1 shared Anthony BeucheriD· 1 shared Brice ChaneziD· 1 shared Cristina BodasiD· 1 shared Diego BalboaiD· 1 shared Evangelina López de MaturanaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Sagrario OrtegaORCID

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2 papers

Recent·Most cited

A common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice

Cristina Bodas, Irene Felipe‐Abrio, Brice Chanez, Miguel Lafarga, Evangelina López de Maturana, Jaime Martínez de Villarreal, Natalia del Pozo, Marina Malumbres, Pierfrancesco Vargiu, Ana Cayuela, Isabel Peset, Katelyn E. Connelly, Jason W. Hoskins, Raúl Méndez, Laufey Thora Amundadottir, , Francisco X. Real

This paper shows a CTRB2 deletion variant increases pancreatic cancer risk by causing ER stress and inflammation in mice, using a new genetic model.

Gut · Apr 19, 2025Peer-reviewedCancer Biology

HASTER is a transcriptional stabilizer of HNF1A

Anthony Beucher, Irene Miguel-Escalada, Diego Balboa, Matías G. De Vas, Miguel Angel Maestro, Javier García-Hurtado, Aina Bernal, Roser Gonzalez-Franco, Pierfrancesco Vargiu, Holger Heyn, Philippe Ravassard, Sagrario Ortega, Jorge P. Ferrer

This study identifies HASTER, a lncRNA that stabilizes HNF1A expression through cis-regulatory mechanisms, and shows its disruption leads to diabetes.

bioRxiv · May 12, 2021 · PreprintGenomics