Author

R. A. Prescott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:protein structure· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

M. de Vries· 3 shared M. Dittmann· 3 shared A. Anderson· 1 shared A. Fisher· 1 shared A. Herrera· 1 shared A. Mohamed· 1 shared A. P. Pankow· 1 shared A. Schinlever· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersMicrobiology

M. de Vries

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Author profile →

3 papers

Recent·Most cited

A comparative study of in vitro air-liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution

R. A. Prescott, A. P. Pankow, M. de Vries, K. Crosse, R. S. Patel, M. Alu, C. Loomis, V. Torres, S. B. Koralov, E. N. Ivanova, M. Dittmann, B. R. Rosenberg

This study compares gene expression and cellular heterogeneity in HAE cultures derived from BCi-NS1.1 cell lines and primary cells using scRNA-Seq, finding similar morphology and transcriptional patterns but some interferon gene differences.

bioRxiv · Feb 27, 2023 · PreprintCell Biology

In-silico docking platform with serine protease inhibitor (SERPIN) structures identifies host cysteine protease targets with significance for SARS-CoV-2

J. J. Rodriguez Galvan, M. de Vries, S. Belblidia, A. Fisher, R. A. Prescott, K. M. Crosse, W. F. Mangel, R. Duerr, M. Dittmann

The paper uses in-silico docking to identify SERPIN targets in SARS-CoV-2, finding novel interactions and validating their role in viral replication.

bioRxiv · Nov 18, 2022 · PreprintMicrobiology

A comparative analysis of SARS-CoV-2 antivirals in human airway models characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19

M. de Vries, A. Mohamed, R. A. Prescott, A. Valero-Jimenez, L. Desvignes, R. O'Connor, C. Steppan, J. C. Devlin, E. Ivanova, A. Herrera, A. Schinlever, P. Loose, K. Ruggles, S. Koralov, A. Anderson, , M. Dittmann

This study compares the antiviral efficacy of PF-00835231, GC-376, and remdesivir in human airway models, showing PF-00835231 is at least as potent as the others and not affected by P-glycoprotein efflux.

bioRxiv · Aug 28, 2020 · PreprintMicrobiology