Author

R. Blasco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Nogales· 3 shared K. Chiem· 3 shared L. Martinez-Sobrido· 3 shared M. M. Lorenzo· 3 shared A. Matia· 2 shared M. Lorenzo· 2 shared A. Zaballos· 1 shared C. Arias· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

A. Nogales

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Spatio-temporal analysis of Vaccinia virus infection and host response dynamics using single-cell transcriptomics and proteomics

A. Matia, F. McCarthy, H. Woosley, V. Turon-Lagot, S. W. Platzer, J. Liu, M. M. Lorenzo, M. Borja, K. Shetty, J. Winkler, J. E. Elias, R. Blasco, C. Arias, M. Y. Hein

This study uses single-cell transcriptomics and proteomics to analyze Vaccinia virus infection dynamics and host response heterogeneity in HeLa and fibroblast cells.

bioRxiv · Jan 13, 2024 · PreprintMicrobiology

Antivirals against monkeypox infections

K. Chiem, A. Nogales, M. M. Lorenzo, D. Morales Vasquez, Y. Xiang, Y. Gupta, R. Blasco, J. C. de la Torre, L. Martinez-Sobrido

This study evaluates 19 compounds for antiviral activity against Orthopoxviruses, identifying 13 with activity against vaccinia virus and 11 with activity against monkeypox virus.

bioRxiv · Apr 19, 2023 · PreprintMicrobiology

Identification of β2 microglobulin, the product of B2M gene, as a Host Factor for Vaccinia Virus Infection by Genome-Wide CRISPR genetic screens

A. Matia, M. M. Lorenzo, Y. C. Romero-Estremera, J. M. Sanchez-Puig, A. Zaballos, R. Blasco

This study identifies β2 microglobulin as a host factor for Vaccinia virus infection through genome-wide CRISPR screens in HeLa cells.

bioRxiv · Aug 10, 2022Microbiology

Vaccinia virus attenuation by codon deoptimization of the A24R gene for vaccine development

M. Lorenzo, A. Nogales, K. Chiem, R. Blasco, L. Martinez-Sobrido

This study attenuates vaccinia virus by codon deoptimization of the A24R gene, creating a safe and protective vaccine candidate against poxvirus infection.

bioRxiv · Jan 23, 2022 · PreprintMicrobiology

Bi-reporter vaccinia virus for tracking viral infections in vitro and in vivo

K. Chiem, M. Lorenzo, J. Rangel-Moreno, M. d. l. L. Garcia-Hernandez, J.-G. Park, A. Nogales, R. Blasco, L. Martinez-Sobrido

This paper introduces bi-reporter vaccinia viruses expressing both fluorescent and luciferase genes to track viral infections in vitro and in vivo, enabling detailed study of infection dynamics and host-pathogen interactions.

bioRxiv · Aug 24, 2021Microbiology