R. Gacesa

High-resolution analysis of the treated coeliac disease microbiome reveals strain-level variation

This study analyzes the gut microbiome of treated coeliac disease patients at strain level, revealing increased interindividual variation and specific microbial associations.

Mother-Infant Gut Viruses and their Bacterial Hosts: Transmission Patterns and Dynamics during Pregnancy and Early Life

The faecal metabolome and its determinants in inflammatory bowel disease

This study identifies metabolic alterations in IBD patients by analyzing faecal metabolites, metagenomics, host genetics, and clinical data, finding over 300 differentially abundant molecules and associations with microbiota and diet.

Mucosal host-microbe interactions associate with clinical phenotypes in inflammatory bowel disease

This study identifies host-microbe interactions in IBD by analyzing transcriptomic and microbial data from intestinal biopsies, linking specific bacteria to gene pathways and clinical phenotypes.

HIV-linked gut dysbiosis associates with cytokine production capacity in viral-suppressed people living with HIV

This study links HIV-associated gut dysbiosis to cytokine production capacity in ART-suppressed PLHIV, identifying specific microbial strains associated with immune markers.

In-depth characterization of the serum antibody epitope repertoire in inflammatory bowel disease using phage-displayed immunoprecipitation sequencing

This study identifies distinct antibody epitope repertoires in IBD patients using PhIP-seq, revealing differentially abundant antibodies associated with disease subtypes and features.

The Dutch Microbiome Project defines factors that shape the healthy gut microbiome

This study identifies environmental and lifestyle factors shaping the gut microbiome in a large Dutch cohort, finding that most microbiome variation is due to environment rather than genetics.