Author

R. S. Weiss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. D. Miller· 1 shared A. Dziubek· 1 shared A. Grimson· 1 shared A. J. M. Gillis· 1 shared A. Latifkar· 1 shared A. R. Loehr· 1 shared A.-Y. Tu· 1 shared C. E. Murry· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperCancer Biology

A. D. Miller

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A TOPBP1 Allele Causing Male Infertility Uncouples XY Silencing Dynamics From Sex Body Formation

C. F. R. Ascencao, J. Sims, A. Dziubek, W. Comstock, E. A. Fogarty, J. Badar, R. Freire, A. Grimson, R. S. Weiss, P. E. Cohen, M. B. Smolka

This study identifies a TOPBP1 mutation causing male infertility by disrupting ATR-dependent MSCI dynamics without affecting SB formation.

eLife · Feb 23, 2024Peer-reviewedCell Biology

Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection

A. R. Loehr, D. M. Timmerman, M. Liu, A. J. M. Gillis, M. D. Matthews, J. C. Bloom, P. K. Nicholls, D. C. Page, A. D. Miller, L. H. J. Looijenga, R. S. Weiss

This study identifies miR-290-295 and miR-371-373 clusters as conserved serum biomarkers for detecting germ cell tumors in mice and humans.

bioRxiv · Sep 9, 2023Cancer Biology

dATP Elevation Induces Myocardial Metabolic Remodeling to Support Improved Cardiac Function

K. N. Mhatre, J. D. Murray, G. Flint, T. S. McMillen, G. Weber, M. Shakeri, A.-Y. Tu, S. Steczina, R. S. Weiss, D. Marcinek, C. E. Murry, D. Raftery, R. Tian, F. Moussavi-Harami, M. Regnier

This study shows that elevating dATP in cardiomyocytes improves cardiac function by enhancing contractility and metabolic flexibility through mitochondrial remodeling.

bioRxiv · Nov 7, 2022Physiology

ATM modulates nuclear mechanics by regulating lamin A levels

P. Shah, C. W. McGuigan, S. Cheng, C. I. Vanpouille-Box, S. Demaria, R. S. Weiss, J. Lammerding

This study shows ATM regulates lamin A levels, affecting nuclear mechanics and cell migration.

bioRxiv · Feb 28, 2022Cell Biology

IGF2BP2 Promotes Cancer Progression by Degrading the RNA Transcript Encoding a v-ATPase Subunit

A. Latifkar, F. Wang, J. J. Mullmann, I. R. Fernandez, L. Ling, C. Fischbach, R. S. Weiss, H. Lin, R. A. Cerione, M. A. Antonyak

The paper shows that IGF2BP2 degradation of ATP6V1A transcript, driven by SIRT1 down-regulation and acetylation, impairs lysosomal function and promotes cancer progression.

bioRxiv · Apr 1, 2021Cell Biology