R. Sengupta

Contribution of the Golgi apparatus in morphogenesis of a virus induced cytopathic vacuolar system

The paper investigates how the Golgi apparatus transforms into cytopathic vacuoles during alphavirus infection using electron tomography and Golgi markers.

Development of Microbiome Biomarkers for IgA: a Joint Modeling Approach

This paper develops a joint model to identify microbiome biomarkers for intestinal IgA levels, finding that S24-7 family diversity and specific OTUs predict IgA responses across treatment groups and timepoints.

SARS-CoV-2 viral budding and entry can be modeled using virus-like particles

This study develops a BSL-2-compatible system using SARS-CoV-2 virus-like particles to model viral budding and entry mechanisms and assess drug inhibitors.

Strategy guides feature recall of a single object in working memory task

This study investigates how repeating feature questions affects recall accuracy in a working memory task, finding that repeated probes degrade recall for both color and location.

Temporal dynamics of ensemble statistics calculation using a neural network model

The paper investigates a neural network model's ability to switch between individuation and summarization of visual scenes, revealing insights into temporal dynamics of ensemble perception.

Recalling a single object: going beyond the capacity debate

This study investigates recall accuracy for features of a single object across three experiments, finding that errors increase with the number of recall questions and question order, challenging slot and resource models of working memory.

N-terminal autoprocessing and acetylation of MARTX Makes-Caterpillars Floppy-like effector is stimulated by ADP-Ribosylation Factor 1 in advance of Golgi fragmentation

This study identifies ARF1 and ARF3 as activators of MCF autoprocessing and shows that MCF acetylation and Golgi fragmentation contribute to cytotoxicity.

Alpha-Synuclein is a Target of Fic-mediated Adenylylation/AMPylation: Implications for Parkinson’s Disease

The paper identifies alpha-Synuclein as a target of HYPE-mediated adenylylation, showing it reduces Syn aggregation and ER stress in Parkinson’s disease models.

CryoAPEX - an electron tomography tool for subcellular localization of membrane proteins

CryoAPEX localizes membrane proteins with high-resolution 3D structural analysis in preserved cellular contexts, showing HYPE is localized in ER subdomains.