NAD Metabolism Drives CTCF-Cohesin Chromatin Regulation in EBV-Transformed B-Cells
Davide Maestri, Rachel Sklutuis, Lisa Beatrice Caruso, Sarah Preston-Alp, Martina Gatto, Samantha S Soldan, Pyounghwa Park, Lauren Melick, Laura Corveleyn, Simone Sidoli, Andrew Kossenkov, Aaron R Goldman, Wujuan Zhang, Hsin-Yao Tang, Giorgia Napoletani, , Italo Tempera
This study shows that NAD metabolism supports CTCF-cohesin chromatin regulation in EBV-transformed B-cells and identifies NAMPT inhibition as a potential therapeutic strategy.
bioRxiv · Nov 2, 2026 · PreprintMicrobiology