Author

Ran Jing

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Organism:zebrafish· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

George Q. DaleyiD· 3 shared Mohamad Ali Toufic NajiaiD· 3 shared Thorsten M. SchlaegeriD· 3 shared Trista E. NorthiD· 3 shared Christopher LiiD· 2 shared Eleanor Meader· 2 shared Marcelo FalchettiiD· 2 shared Morgan T. WalcheckiD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

George Q. DaleyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Flow-Induced Yap/Taz Signaling Balances Endothelial and Hematopoietic Stem Cell Fates

Wade W. Sugden, Stephan George, Zachary C. LeBlanc, Morgan T. Walcheck, Eleanor Meader, Julia Goldstein, Elizabeth Molnar, Wandi Zhu, Rubul Mout, Christopher Li, Leah Radeke, Zoey Young, Maria Gonzalez di Tillio, Marcelo Falchetti, Mohamad Ali Toufic Najia, , Trista E. North

This study shows that hemodynamic forces activate YAP signaling via Piezo1 in hemogenic endothelium, promoting HSC production by regulating metabolic and gene regulatory programs, while TAZ overactivation disrupts this balance.

bioRxiv · Jun 23, 2026 · PreprintCell Biology

Bnip3lb-driven mitophagy sustains expansion of the embryonic hematopoietic stem cell pool

Eleanor Meader, Morgan T. Walcheck, Mindy Leder, Patrice Delaney, Marcelo Falchetti, Ran Jing, Christopher Li, Netra K. Kambli, Paul J. Wrighton, Wade W. Sugden, Mohamad Ali Toufic Najia, Isaac M. Oderberg, Vivian M. Taylor, Zachary C. LeBlanc, Eleanor D. Quenzer, , Trista E. North

This study shows that Bnip3lb-driven mitophagy maintains embryonic HSPC multipotency and expansion by regulating ROS levels, and enhances ex vivo hematopoietic potential of iPSC-derived HSPCs.

Nature Communications · Feb 24, 2026Peer-reviewedCell Biology

Engineering a mouse-adapted SADS-CoV and establishing a neonatal mouse model to study its infection

Hanyu Zhang, Jiaru Zhou, Pengfei Li, Mengdi Zhang, Ran Jing, Hongmei Zhu, Yifei Lang, Qigai He, Mengjia Zhang, Wentao Li

This paper creates a mouse-adapted SADS-CoV virus and a neonatal mouse model to study its infection and evaluate antiviral treatments.

mBio · Jan 12, 2026Peer-reviewedMicrobiology

Design of a Soluble Multivalent Notch Agonist

Rubul Mout, Ran Jing, Emily D. Egan, Helen E. Eisenach, Mohamad Ali Toufic Najia, Luca T. Hensch, Trevor Bingham, Martin A. Kononov, Rajesh D. Gunage, Yunliang Zhao, Natasha I. Edman, Thorsten M. Schlaeger, Leonard Ira Zon, Trista E. North, Urban Lendahl, , George Q. Daley

This paper designs soluble multivalent Notch agonists to activate Notch signaling in vitro, enabling T cell differentiation and immunotherapy development.

bioRxiv · Aug 7, 2024 · PreprintSynthetic Biology