Author

Rico Barsacchi

Max Planck Institute of Molecular Cell Biology and Genetics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alon Minkovich· 1 shared Anthony A. HymaniD· 1 shared Antje Janosch· 1 shared Carina A. Lyons· 1 shared Claudia Möbius· 1 shared Daniel E. StangeiD· 1 shared Eileigh Kadijk· 1 shared Frank BuchholziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Alon Minkovich

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2 papers

Recent·Most cited

Loss of UBP1 drives oxaliplatin resistance through a targetable dependency on translation initiation

Moustafa Abohawya, Tim Schmäche, Julia Dietzel, Ina Hollerer, Li Ding, Maciej Paszkowski‐Rogacz, Rico Barsacchi, Therese Seidlitz, Sebastián García Tobar, Frank Buchholz, Daniel E. Stange, Jovan Mirectic

The paper identifies UBP1 loss as a driver of oxaliplatin resistance in gastric cancer by revealing a compensatory reliance on translation initiation, which can be targeted with 4EGI.

bioRxiv · May 20, 2026 · PreprintCancer Biology

Stress Granule Sequestration of CCR4-NOT Promotes Poly(A) Lengthening of Stress-Survival Transcripts

Yi-Cheng Tsai, Hiroyuki Uechi, Sean R. Millar, Eileigh Kadijk, Alon Minkovich, John Paul Tsu Ouyang, Karl J. Schreiber, Jie Qi Huang, Carina A. Lyons, Vesal Kasmaeifar, Zhixin Zhang, Rico Barsacchi, Claudia Möbius, Antje Janosch, Jonathan C. Savage, , Ji‐Young Youn

The paper shows that stress granules sequester the CCR4-NOT complex, leading to poly(A) tail lengthening and increased survival transcript abundance under stress.

bioRxiv · Feb 4, 2025 · PreprintCell Biology