Author

Roland Schmucki

F. Hoffmann-La Roche AG

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:batch correction / integration· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Martin EbelingiD· 3 shared Jitao David ZhangiD· 2 shared Albert S. W. KangiD· 1 shared Alice Julien-LaferrièreiD· 1 shared Anne SpangiD· 1 shared Anthony SonreliD· 1 shared Arne WehlingiD· 1 shared Benjamin HaleyiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBioinformatics

Martin EbelingORCID

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Author profile →

4 papers

Recent·Most cited

A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular ASO activity

Liza Malong, Jessica Roskosch, Carolina Hager, Jean‐Philippe Fortin, Roland Schmucki, Marinella G. Callow, Christian Weile, Valentina Romeo, Christoph Patsch, Scott E. Martin, Mike Costa, Zora D. Modrusan, Roberto Villaseñor, Erich Koller, Benjamin Haley, , Filip Roudnicky

The paper uses a CRISPR/Cas9 screen to identify genes modulating ASO activity, revealing AP1M1 and TBC1D23 as key regulators of endosome-Golgi transport affecting ASO efficacy.

Nature Communications · Jun 30, 2025Peer-reviewedCell Biology

splicekit: a comprehensive toolkit for splicing analysis from short-read RNA-seq

Gregor Rot, Arne Wehling, Roland Schmucki, Nikolaos Berntenis, Jitao David Zhang, Martin Ebeling

splicekit provides tools for splicing analysis from short-read RNA-seq data, including alignment, alternative splicing detection, motif discovery, and visualization.

bioRxiv · May 25, 2023 · PreprintBioinformatics

Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research

Sophia Clara Mädler, Alice Julien-Laferrière, Luis Wyss, Miroslav Phan, Anthony Sonrel, Albert S. W. Kang, Eric Ulrich, Roland Schmucki, Jitao David Zhang, Martin Ebeling, Laura Badi, Tony Kam‐Thong, Petra Catalina Schwalie, Klas Hatje

Besca is a toolkit that streamlines scRNA-seq analysis with quality control, clustering, cell annotation, and bulk transcriptomics integration across datasets.

NAR Genomics and Bioinformatics · Oct 4, 2021Peer-reviewedBioinformatics

Draft genome of the Eutardigrade Milnesium tardigradum sheds light on ecdysozoan evolution

Felix Bemm, Laura Burleigh, Frank Förster, Roland Schmucki, Martin Ebeling, Christian J. Janzen, Thomas Dandekar, Ralph O. Schill, Ulrich Certa, Jörg Schultz

This study presents the first draft genome of Milnesium tardigradum, revealing gene loss and stress response mechanisms, and clarifying its phylogenetic position within Ecdysozoa.

bioRxiv · Sep 5, 2017 · PreprintEvolutionary Biology