Author

Valentina Romeo

F. Hoffmann-La Roche AGORCID 0000-0001-8475-5950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Anne SpangiD· 1 shared Benjamin HaleyiD· 1 shared Carolina Hager· 1 shared Christian WeileiD· 1 shared Christoph PatschiD· 1 shared Erich KolleriD· 1 shared Filip RoudnickyiD· 1 shared Jean‐Philippe FortiniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Anne SpangORCID

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1 paper

Recent·Most cited

A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular ASO activity

Liza Malong, Jessica Roskosch, Carolina Hager, Jean‐Philippe Fortin, Roland Schmucki, Marinella G. Callow, Christian Weile, Valentina Romeo, Christoph Patsch, Scott E. Martin, Mike Costa, Zora D. Modrusan, Roberto Villaseñor, Erich Koller, Benjamin Haley, , Filip Roudnicky

The paper uses a CRISPR/Cas9 screen to identify genes modulating ASO activity, revealing AP1M1 and TBC1D23 as key regulators of endosome-Golgi transport affecting ASO efficacy.

Nature Communications · Jun 30, 2025Peer-reviewedCell Biology