Author

Rosa Di Leo

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:yeast· 1

Frequent Co-Authors

Alexei V. SavchenkoiD· 2 shared Bradley QuadeiD· 1 shared Chester PhamiD· 1 shared D. Peter TielemaniD· 1 shared David H. KwaniD· 1 shared Dominika BorekiD· 1 shared Elina M. KarimullinaiD· 1 shared Hanif Muhammad KhaniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Alexei V. SavchenkoORCID

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2 papers

Recent·Most cited

Structural architecture of TolQ-TolR inner membrane protein complex from opportunistic pathogen Acinetobacter baumannii

Elina M. Karimullina, Yirui Guo, Hanif Muhammad Khan, Tabitha Emde, Bradley Quade, Rosa Di Leo, Zbyszek Otwinowski, D. Peter Tieleman, Dominika Borek, Alexei V. Savchenko

The paper presents cryo-EM structures of the TolQ-TolR complex from Acinetobacter baumannii, revealing structural changes related to PMF energy transfer and cell envelope organization.

Science Advances · Apr 4, 2025Peer-reviewedMolecular Biology

Functional and Structural Characterization of an IclR Family Transcription Factor for the Development of Dicarboxylic Acid Biosensors

Chester Pham, Mohamed A. Nasr, T. Skarina, Rosa Di Leo, David H. Kwan, Vincent J. J. Martin, P.J. Stogios, Radhakrishnan Mahadevan, Alexei V. Savchenko

This paper characterizes the PcaR transcription factor, solving its crystal structures and demonstrating its function as a dicarboxylic acid biosensor in yeast.

FEBS Journal · May 2, 2024Peer-reviewedSynthetic Biology