Yifei Liao

This study shows that NAD metabolism supports CTCF-cohesin chromatin regulation in EBV-transformed B-cells and identifies NAMPT inhibition as a potential therapeutic strategy.

This study uses a genome-wide CRISPR-Cas9 screen to identify host factors essential for EBV B cell infection, revealing new pathways and potential therapeutic targets.

This study shows that methionine restriction induces ferroptosis in EBV-transformed B cells by promoting transsulfuration and glutathione synthesis, and that targeting methionine metabolism can impair tumor growth.

This study identifies JunB as a key dependency factor in EBV-infected B cells that represses p18INK4c, revealing a potential therapeutic target for EBV-associated cancers.

This paper identifies STEEP1 as a host factor critical for LMP1 trafficking and signaling using a CRISPR-Cas9 screen, showing its role in NF-kB and MAP kinase pathway activation.

This study identifies viral lncRNAs that regulate EBV reactivation by interacting with CTCF and modulating enhancer-promoter looping.