Author

Ruidong Guo

BGI Group (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Genetic & Genomic Medicine· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:metagenomics· 3 Research Focus:cell type annotation· 2 Research Focus:database / resource· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Huijue JiaiD· 3 shared Jian WangiD· 2 shared Lili Li· 2 shared Qiaoxing LiangiD· 2 shared Xihong LaniD· 2 shared Xun XuiD· 2 shared Canqing YuiD· 1 shared Changling Zhang· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

Huijue JiaORCID

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5 papers

Recent·Most cited

Precision culturomics enabled by unlabeled single-cell morphology and Raman spectra

Qiaoxing Liang, Xihong Lan, Jiayi Wu, Wei Wei, Lili Li, Xiaofang Tang, Guoping Zhao, Ruidong Guo, Huijue Jia

This paper introduces a precision culturomics method using single-cell morphology and Raman spectra to sort and analyze microbial cells, revealing antibiotic-driven resistance and mutations in gut commensals.

Nature Communications · Jun 20, 2026Peer-reviewedMicrobiology

Microbial single-cell omics in situ

Xihong Lan, Qiaoxing Liang, JINHUA HE, Jiang Wu, Xiaoying Zhang, Fei Li, Lili Li, Guoping Zhao, Ruidong Guo, Huijie Jia

The paper reports a method using LIFT technology to obtain high-quality microbial single-cell genomes or transcriptomes from complex samples and demonstrates its application to study cell-fate commitment in sporulation.

Cell Genomics · Jan 22, 2026Peer-reviewedMicrobiology

Sequencing-based Spatial Transcriptomics with scRNA-seq Sensitivity

Renjie Liao, Defeng Fu, Zaoxu Xu, Han Liang, Xiaoran Zhou, Yiling Elaine Chen, Xue‐Qi Liu, Ji Cheng, Ruidong Guo, Li Chen, Huihua Xia, Gailing Li, Diewen Feng, Wei Chen, Yang Chen, , Gufeng Wang

This paper introduces a sequencing-based spatial transcriptomics system with sub-cellular resolution and significantly improved capture efficiency compared to existing methods.

bioRxiv · Jan 15, 2025 · PreprintMolecular Biology

A High-resolution Haplotype-resolved Reference Panel Constructed from the China Kadoorie Biobank Study

Canqing Yu, Xianmei Lan, Ye Tao, Yu Guo, Dianjianyi Sun, Puyi Qian, Yuwen Zhou, Robin G. Walters, Linxuan Li, Yunqing Zhu, Jingyu Zeng, Iona Y. Millwood, Ruidong Guo, Pei Pei, Tao Yang, , Liming Li

The paper constructs a high-resolution haplotype-resolved reference panel from the China Kadoorie Biobank study and demonstrates its superior performance in imputing microarray data compared to existing panels.

Nucleic Acids Research · Oct 23, 2023Peer-reviewedGenetic & Genomic Medicine

M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases

Xiaomin Liu, Shanmei Tang, Huanzi Zhong, Xin Tong, Zhuye Jie, Qiuxia Ding, Dan Wang, Ruidong Guo, Liang Xiao, Xun Xu, Huanming Yang, Jian Wang, Yang Zong, Weibin Liu, Xiao Liu, , Tao Zhang

This paper performs M-GWAS on a Chinese cohort to identify genetic contributions to the gut microbiome and its associations with complex diseases.

Cell Discovery · Feb 9, 2021Peer-reviewedGenetics