Author

S. Chothani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. A. Widjaja· 1 shared A. Clerk· 1 shared A. Hearn· 1 shared B. K. Singh· 1 shared B. NG· 1 shared C. L. Drum· 1 shared D. N. Meijles· 1 shared E. Adami· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

A. A. Widjaja

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2 papers

Recent·Most cited

Striatin plays a major role in angiotensin II-induced cardiomyocyte and cardiac hypertrophy in mice in vivo.

J. J. Cull, S. T. Cooper, H. O. Alharbi, S. Chothani, O. J. Rackham, D. N. Meijles, P. R. Dash, R. Kerkela, N. Ruparelia, P. H. Sugden, A. Clerk

This paper shows that striatin (STRN) in cardiomyocytes is necessary for angiotensin II-induced cardiac hypertrophy and remodelling in mice, but not STRN3.

bioRxiv · Oct 21, 2023 · PreprintPhysiology

Redefining Interleukin 11 as a regeneration-limiting hepatotoxin

A. A. Widjaja, J. R. Dong, E. Adami, S. Viswanathan, B. NG, B. K. Singh, W.-W. Lim, J. Zhou, L. S. Pakkiri, S. G. Shekeran, J. Tan, S. Y. Lim, M. Wang, R. Holgate, A. Hearn, , S. A. Cook

This study reveals IL11 as a hepatotoxin that limits liver regeneration after APAP overdose, showing its inhibition of endogenous IL11 activity protects mice.

bioRxiv · Nov 4, 2019Physiology