Author

S. E. Coupland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:clinical cohort / trial· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. Phiri· 2 shared H. Kalirai· 2 shared I. Bates· 2 shared M. Boele van Hensbroek· 2 shared T. J. Allain· 2 shared A. B. Heeran· 1 shared A. G. Jochemsen· 1 shared A. Groenewoud· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

C. Phiri

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Patient-derived zebrafish xenograft models reveal ferroptosis as a fatal and druggable weakness in metastatic uveal melanoma

A. Groenewoud, J. Yin, M. C. Gelmi, S. Alsafadi, F. Nemati, D. Decaudin, S. Roman-Roman, H. Kalirai, S. E. Coupland, A. G. Jochemsen, M. J. Jager, E. Snaar-Jagalska

The paper develops a zebrafish xenograft model of metastatic uveal melanoma and identifies ferroptosis as a druggable vulnerability in tumors with BAP1 loss.

bioRxiv · Oct 26, 2021 · PreprintCancer Biology

High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells.

K. Slater, A. B. Heeran, R. Sanz-Pamplona, H. Kalirai, A. Rahman, M. Helmi, S. Garcia-Mulero, F. O'Connell, R. Bosch, A. Portela, A. Villanueva, J. M. Piulats, W. M. Gallagher, L. D. Jensen, S. E. Coupland, , B. N. Kennedy

This paper shows high CysLT1 receptor expression in uveal melanoma correlates with poor survival and that CysLT1 antagonists inhibit tumor growth and alter cancer secretome and metabolism.

bioRxiv · Aug 23, 2020Cancer Biology

Hepcidin and conventional markers to detect iron deficiency in severely anaemic HIV-infected patients in Malawi.

M. N. Huibers, J. Calis, T. J. Allain, S. E. Coupland, C. Phiri, K. Phiri, D. W. Swinkels, M. Boele van Hensbroek, I. Bates

This study evaluates hepcidin and conventional markers for detecting bone-marrow iron deficiency in severely anaemic HIV-infected patients in Malawi, finding hepcidin to be the best, though still suboptimal, marker.

bioRxiv · Jun 10, 2019Biochemistry

Severe anaemia complicating HIV in Malawi; multiple co-existing aetiologies are associated with high mortality.

M. N. H. W. Huibers, I. Bates, S. Mckew, T. J. Allain, S. E. Coupland, C. Phiri, K. S. Phiri, M. Boele van Hensbroek, J. C. Calis

This study identifies multiple co-existing causes of severe anaemia in HIV-infected adults in Malawi and links them to high mortality.

bioRxiv · Jun 10, 2019Immunology