Author

S. Roman-Roman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Decaudin· 2 shared F. Nemati· 2 shared A. Brisson· 1 shared A. E. Tijhuis· 1 shared A. G. Jochemsen· 1 shared A. Groenewoud· 1 shared A. Herbette· 1 shared A. Nicolas· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

D. Decaudin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions

F. Edwards, G. Fantozzi, A. Y. Simon, J.-P. Morretton, A. Herbette, A. E. Tijhuis, R. Wardenaar, S. Foulane, S. Gemble, D. C. J. Spierings, F. Foijer, O. Mariani, A. Vincent-Salomon, S. Roman-Roman, X. Sastre-Garau, , R. Basto

The paper shows centrosome amplification in ovarian cancer cells primes them for apoptosis and improves chemotherapy response, independent of multipolar divisions and chromosome instability.

bioRxiv · Jul 28, 2023 · PreprintCell Biology

Patient-derived zebrafish xenograft models reveal ferroptosis as a fatal and druggable weakness in metastatic uveal melanoma

A. Groenewoud, J. Yin, M. C. Gelmi, S. Alsafadi, F. Nemati, D. Decaudin, S. Roman-Roman, H. Kalirai, S. E. Coupland, A. G. Jochemsen, M. J. Jager, E. Snaar-Jagalska

The paper develops a zebrafish xenograft model of metastatic uveal melanoma and identifies ferroptosis as a druggable vulnerability in tumors with BAP1 loss.

bioRxiv · Oct 26, 2021 · PreprintCancer Biology

PRMT1 regulates EGFR and Wnt signaling pathways and is a promising target for combinatorial treatment of breast cancer

S. Suresh, S. Huard, A. Brisson, F. Nemati, C. Poulard, M. Ye, E. Martel, C. Reyes, D. C. Silvestre, D. Meseure, A. Nicolas, D. Gentien, M. Le Romancer, D. Decaudin, S. Roman-Roman, T. Dubois

This study identifies PRMT1 as a key regulator of EGFR and Wnt signaling in breast cancer and shows that targeting it with inhibitors can enhance chemotherapy and EGFR inhibitor efficacy in TNBC.

bioRxiv · Oct 22, 2021Cancer Biology