Author

S. E. Crawford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:variant calling· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. K. Estes· 4 shared B. V. Ayyar· 2 shared F. H. Neill· 2 shared F. Stossi· 2 shared K. Ettayebi· 2 shared R. L. Atmar· 2 shared S. Ramani· 2 shared V. R. Tenge· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersMicrobiology

M. K. Estes

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Bile acid-sensitive human norovirus strains are susceptible to sphingosine-1-phosphate receptor 2 inhibition

V. R. Tenge, B. V. Ayyar, K. Ettayebi, S. E. Crawford, Y.-T. Shen, F. H. Neill, R. L. Atmar, M. K. Estes

This study shows that BA-dependent human norovirus strains require S1PR2 for infection, while BA-independent strains do not, suggesting S1PR2 as a potential therapeutic target.

bioRxiv · Jan 2, 2024Microbiology

RNA-dependent RNA polymerase of predominant human norovirus forms liquid-liquid phase condensates as viral replication factories

S. Kaundal, A. Ramakrishnan, B. V. Ayyar, S. Shanker, G. Kaur, S. E. Crawford, J. Pollet, F. Stossi, M. K. Estes, B. V. V. Prasad

bioRxiv · Aug 24, 2023 · PreprintBiochemistry

Infant and Adult Human Intestinal Enteroids are Morphologically and Functionally Distinct

G. O. Adeniyi-Ipadeola, J. D. Hankins, A. Kambal, X.-L. Zeng, K. Patil, V. Poplaski, C. Bomidi, H. Nguyen-Phuc, S. L. Grimm, C. Coarfa, F. Stossi, S. E. Crawford, S. E. Blutt, A. L. Speer, M. K. Estes, S. Ramani

This study compares infant and adult human intestinal enteroids, finding significant transcriptomic, morphological, and functional differences that highlight their distinct characteristics.

bioRxiv · May 19, 2023Microbiology

100 years of anthropogenic impact causes changes in freshwater functional biodiversity

N. Eastwood, J. Zhou, R. Derelle, M. A.-E. Abdallah, W. A. Stubbings, Y. Jia, S. E. Crawford, T. A. Davidson, J. K. Colbourne, S. Creer, H. Bik, H. Hollert, L. Orsini

The paper uses AI to analyze 100 years of freshwater biodiversity data, showing that insecticides, fungicides, and climate factors explain most functional biodiversity changes.

bioRxiv · Feb 26, 2023Ecology

TNF Blockade Reduces Prostatic Hyperplasia and Inflammation while Limiting BPH Diagnosis in Patients with Autoimmune Disease

R. E. Vickman, L. Aaron-Brooks, R. Zhang, N. A. Lanman, B. Lapin, V. Gil, M. Greenberg, T. Sasaki, G. M. Cresswell, M. M. Broman, J. Petkewicz, P. Talaty, B. T. Helfand, A. P. Glaser, C.-H. Wang, , S. W. Hayward

Patient data and mouse models suggest that repurposing tumor necrosis factor alpha blockade reduces inflammation-mediated prostatic hyperplasia.

bioRxiv · Mar 11, 2021Cell Biology

New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids

K. Ettayebi, V. R. Tenge, N. W. Cortes-Penfield, S. E. Crawford, F. H. Neill, X.-L. Zeng, X. Yu, V. B. Ayyar, D. Burrin, S. Ramani, R. L. Atmar, M. K. Estes

This paper optimizes human intestinal enteroid culture conditions to enhance cultivation of diverse human norovirus strains and improves replication consistency over time.

bioRxiv · Nov 12, 2020Microbiology