S. He

The paper shows PSGL-1 inhibits SARS-CoV and SARS-CoV-2 spike glycoprotein incorporation into pseudovirions, blocking virus attachment and infectivity.

This study shows that SIRT1 reduces premature senescence-induced defenestration in hepatic sinusoidal endothelial cells by deacetylating p53 and mitigating oxidative damage.

This study shows that promoters and transcription factors coevolve antagonistically in animals and mutually in plants, leading to different transcriptional network transitions.

This study identifies MeSSII's role in cassava starch biosynthesis by forming protein complexes with other enzymes, affecting amylose and amylopectin synthesis.

Sulfopin, a selective Pin1 inhibitor, reduces tumor initiation and growth in neuroblastoma models by targeting c-Myc pathways.

The paper constructs an adult human cell atlas from 84,363 cells across 15 organs, identifying 252 cell subtypes and revealing inter- and intra-organ heterogeneity.

This paper shows that the seminal peptide PAP248-286 forms peptide/lipid co-aggregates called messicles, which assemble faster and under different conditions than amyloid fibrils.

This study shows that the in vitro and in vivo cellular uptake and trafficking of miktoarm copolymer nanomicelles (MCNs) correlate, with FRET efficiency changes reflecting transport mechanisms and probe uptake behavior.

The paper investigates how mRNAs are recruited into C. elegans P granules through a sequence-independent mechanism involving MEG-3, revealing similarities to stress granules.

This study shows that engineering CAR-T cells with CD103 improves their anti-tumor efficacy against E-cadherin positive tumors by enhancing infiltration, expansion, and persistence in vivo.

This study monitors cytokine dynamics in mouse infection models and evaluates their diagnostic performance for bacterial bloodstream infections.

This study shows KGF induces podosome formation in HIOECs through integrin-Erk1/2 signaling, enhancing epithelial adhesion and rete peg elongation.

This study designs a universal primer set for CAOB amoA genes and reveals their ubiquity and high abundance across diverse ecosystems.

This paper produces transgenic cassava with high amylose starch by silencing BE1 or BE2 genes, showing differences in starch properties between the two gene silencing lines.

The paper proposes a framework integrating D-trace loss with compositional data analysis to improve network and differential network inference from microbial data.

The paper shows that H1 depletion in Arabidopsis thaliana vegetative cells allows DNA demethylation and transposon activation through DEMETER access.

The paper introduces NATF, a method using CRISPR/Cas9 and split-GFP to achieve bright, tissue-specific protein labeling in C. elegans.

This paper develops a human antibody cocktail, MBP134, that provides broad protection against multiple ebolaviruses, showing enhanced efficacy in guinea pigs compared to individual antibodies.

This paper demonstrates that a two-antibody cocktail (MBP134AF) provides broad therapeutic protection against multiple ebolaviruses in ferrets and nonhuman primates.

The paper compares metagenomes from humic and clearwater lakes to show higher extracellular electron transfer gene abundance in humic bogs, suggesting HS as an overlooked electron acceptor in pelagic respiration.

This study shows that p53 loss decreases single-cell motility and invasion in 2-D and 3-D assays, but promotes collective cellular migration in spheroids.

This study demonstrates that acI Actinobacteria can synthesize retinal and assemble functional actinorhodopsins for proton pumping using genomic and heterologous expression analyses.

The paper links freshwater carbon and nutrient cycles by analyzing microbial population genomes and marker genes from two aquatic environments, showing co-occurrence of metabolic pathways and taxonomic patterns.

The paper shows human serum kills commensal Enterococcus faecium but not clinical isolates, mediated by hGIIA, highlighting a potential mechanism for hGIIA resistance in clinical strains.

This study recovers 19 Verrucomicrobia draft genomes from freshwater metagenomes to explore their ecophysiology and role in carbon cycling.