Author

S. L. Gerson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. B. Desai· 4 shared J. N. P. Smith· 4 shared S. D. Markowitz· 4 shared K. F. Christo· 3 shared A. Jogasuria· 2 shared D. M. Dawson· 2 shared A. P. Jogasuria· 1 shared A. V. Broncano· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersImmunology

A. B. Desai

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mast Cell Derived Histamine Negatively Regulates Hematopoiesis

B. R. Klein, J. N. P. Smith, R. Katabathula, R. Chaudhary, Z. Gao, B. A. Cordova, F. Petroze, R. Tiwari, S. L. Gerson, R. Xu, S. D. Markowitz, A. B. Desai

This study shows mast cell-derived histamine suppresses hematopoietic stem cell function, as evidenced by increased hematopoiesis in histamine-deficient mice and reversal with exogenous histamine.

bioRxiv · Feb 3, 2022Immunology

15-PGDH Regulates Hematopoietic and Gastrointestinal Fitness During Aging

W. J. Ho, J. N. P. Smith, Y. S. Park, M. Hadiono, K. F. Christo, A. Jogasuria, Y. Zhang, A. V. Broncano, L. Kasturi, D. M. Dawson, S. L. Gerson, S. D. Markowitz, A. B. Desai

This study shows that 15-PGDH inhibition improves hematopoietic and gastrointestinal tissue fitness in aged mice by enhancing regeneration and reducing inflammation.

bioRxiv · Dec 22, 2020 · PreprintPathology

15-PGDH Inhibition Activates the Splenic Niche to Promote Hematopoietic Regeneration

J. N. P. Smith, D. M. Dawson, K. F. Christo, A. P. Jogasuria, M. J. Cameron, M. I. Antczak, J. M. Ready, S. L. Gerson, S. D. Markowitz, A. B. Desai

This study shows that inhibiting 15-PGDH enhances splenic support for hematopoietic stem and progenitor cells, improving hematopoietic regeneration after bone marrow transplantation.

bioRxiv · Sep 17, 2020Cell Biology

Inhibition of 15-PGDH Protects Mice from Immune-mediated Bone Marrow Failure

J. N. P. Smith, F. Otegbeye, A. Jogasuria, K. F. Christo, S. L. Gerson, S. D. Markowitz, A. B. Desai

This study shows that inhibiting 15-PGDH with SW033291 improves hematologic recovery and survival in a murine model of immune-mediated bone marrow failure.

bioRxiv · Apr 7, 2020Immunology