Author

J. M. Ready

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

M. I. Antczak· 2 shared A. B. Desai· 1 shared A. Churchyard· 1 shared A. K. Lawong· 1 shared A. Kumar· 1 shared A. P. Jogasuria· 1 shared B. A. Posner· 1 shared B. Crespo-Fernandez· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

M. I. Antczak

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules

T. P. Nguyen, M. Fang, J. Kim, B. Wang, E. Lin, V. Khivansara, N. Barrows, G. Rivera-Cancel, M. Goralski, C. L. Cervantes, S. Xie, J. M. Peterson, J. M. Povedano, M. I. Antczak, B. A. Posner, , D. Nijhawan

This study develops an inducible mismatch repair system to identify targets of orphan cytotoxins by screening for compound resistance mutations in engineered cell lines.

bioRxiv · Feb 21, 2023Biochemistry

A fast-killing tyrosine amide ((S)-SW228703) with blood and liver-stage antimalarial activity associated with the Cyclic Amine Resistance Locus (PfCARL)

L. S. Imlay, A. K. Lawong, S. Gahalawat, A. Kumar, C. Xing, N. Mittal, S. Wittlin, A. Churchyard, H. Niederstrasser, B. Crespo-Fernandez, B. Posner, F.-J. S. Gamo, J. Baum, E. Winzeler, B. Laleu, , M. A. Phillips

This paper identifies (S)-SW228703, a tyrosine amide with fast-killing antimalarial activity against blood and liver stages of Plasmodium falciparum, and links resistance to mutations in PfCARL and PfACT.

bioRxiv · Oct 16, 2022Microbiology

15-PGDH Inhibition Activates the Splenic Niche to Promote Hematopoietic Regeneration

J. N. P. Smith, D. M. Dawson, K. F. Christo, A. P. Jogasuria, M. J. Cameron, M. I. Antczak, J. M. Ready, S. L. Gerson, S. D. Markowitz, A. B. Desai

This study shows that inhibiting 15-PGDH enhances splenic support for hematopoietic stem and progenitor cells, improving hematopoietic regeneration after bone marrow transplantation.

bioRxiv · Sep 17, 2020Cell Biology