Author

S. M. Goodfellow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

S. B. Bradfute· 2 shared A. G. Lopez· 1 shared A. Jaberi· 1 shared A. Jimenez Hernandez· 1 shared A. K. Chemel· 1 shared A. Le· 1 shared A. Lopez· 1 shared A. Pradhananga· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

S. B. Bradfute

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic depletion studies define receptor usage by virulent hantaviruses in human endothelial cells

M. E. Dieterle, C. Sola-Riera, R. K. Jangra, C. Ye, S. M. Goodfellow, E. Mittler, E. Kasikci, S. B. Bradfute, J. Klingström, K. Chandran

This study uses CRISPR/Cas9 to knock out potential hantavirus receptors in human endothelial cells, finding that PCDH1 is critical for some hantaviruses while other receptors like integrins and DAF are not essential.

bioRxiv · Dec 30, 2020Microbiology

Non-autophagy role of Atg5 and NBR1 in unconventional secretion of IL-12 prevents gut dysbiosis and inflammation

E. F. Castillo, S. D. Merkley, S. M. Goodfellow, Y. Guo, Z. E. R. Wilton, J. R. Byrum, K. C. Schwalm, D. L. Dinwiddie, R. R. Gullapalli, V. P. Deretic, A. Jimenez Hernandez, S. B. Bradfute, J. G. In

This study shows that Atg5 in intestinal myeloid cells limits IL-12 secretion, preventing dysbiosis and inflammation by reducing IFN-gamma production.

bioRxiv · Dec 7, 2020Immunology

CpG-creating Mutations are Costly in Many Human Viruses

V. R. Caudill, S. Qin, R. Winstead, J. Kaur, K. Tisthammer, E. G. Pineda, O. Carja, R. M. Eggo., K. Koelle, K. Lythgoe, S. Roy, N. Allen, M. Aviles, B. A. Baker, W. Bauer, , Wint

The paper examines the cost of CpG-creating mutations in various human viruses using existing genomic data and finds they are generally costly.

bioRxiv · Jul 25, 2019Evolutionary Biology