Author

S. Khanna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biophysics· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Shivashankar· 2 shared B. S. Choudhary· 2 shared N. Chaudhary· 2 shared N. Verma· 2 shared S. Manna· 2 shared A. L. Ferguson· 1 shared A. Radakovic· 1 shared A. T.-H. Lee· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Shivashankar

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

EGFR-to-Src family tyrosine kinase switching in proliferating-DTP TNBC cells creates a hyperphosphorylation-dependent vulnerability to EGFR TKI

N. Chaudhary, B. S. Choudhary, A. Shivashankar, S. Manna, K. Ved, S. E. Shaikh, S. Khanna, J. Barr, J. Dani, N. Verma

This study identifies a hyper-phosphorylation state in drug-resistant TNBC cells caused by EGFR-to-Src kinase switching, making them vulnerable to EGFR TKI treatment.

bioRxiv · Jul 17, 2023Cancer Biology

GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibition.

N. Chaudhary, B. S. Choudhary, S. Patra, S. Malvankar, A. Shivashankar, E. Jog, V. K. Kailaje, S. Khanna, S. Manna, S. Sahoo, S. R, M. K. Jolly, S. N. Dalal, N. Verma

The paper identifies a proliferating DTP state in TNBC subtypes that is vulnerable to autophagy and glutathione inhibition, linking GPX4-VIM expression to survival outcomes.

bioRxiv · May 18, 2023 · PreprintCancer Biology

Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs

B. Ashwood, M. S. Jones, A. Radakovic, S. Khanna, Y. Lee, J. R. Sachleben, J. W. Szostak, A. L. Ferguson, A. Tokmakoff

This study measures the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization using infrared spectroscopy and simulations, revealing stabilization through stacking interactions and structural dynamics.

bioRxiv · Apr 10, 2023Biophysics

Sustained pigmentation causes DNA damage and invokes translesion polymerase Pol κ for repair in melanocytes

V. Natarajan, S. Khanna, M. Ghazi, Y. J. Subramaniam, I. Gupta, F. Sultan, K. Sharma, S. Chandna, R. S. Gokhale

This study shows sustained melanogenesis causes DNA damage in melanocytes, invokes Pol κ for repair, and links Pol κ activity to genome instability and mutational load in melanoma.

bioRxiv · May 20, 2022 · PreprintCell Biology

Medial septum neurokinin- and somatostatin-sensitive mechanisms mediate sensorimotor and nociceptive behaviours

S. Y. Ng, A. T.-H. Lee, M. Z. Ariffin, P. J. Woon, T. S. H. Chng, S. Khanna

This study investigates the role of neurokinin-1 and somatostatin receptors in the medial septum's influence on sensorimotor and nociceptive behaviors using electrophysiological and behavioral assays.

bioRxiv · Oct 27, 2020 · PreprintNeuroscience

Effects of substituents on anticancer activity of thiosemicarbazone against MCF-7 human breast cancer cell line

B. Z. Sibuh, P. Taneja, S. Khanna

This study evaluates the in-vitro anticancer activity of various thiosemicarbazones against MCF-7 breast cancer cells and normal MCF-10 cells, finding dose- and substituent-dependent effects with some compounds showing selectivity.

bioRxiv · Feb 19, 2020Cancer Biology