Author

M. Puray-Chavez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. B. Kutluay· 4 shared H. R. Vuong· 3 shared S. L. Brody· 3 shared A. Horani· 2 shared C. Shema Mugisha· 2 shared D. Goldfarb· 2 shared J. E. Eschbach· 2 shared K. Tenneti· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

S. B. Kutluay

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Author profile →

4 papers

Recent·Most cited

A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

M. Puray-Chavez, J. E. Eschbach, M. Xia, K. LaPak, Q. Zhou, R. Jasuja, J. Pan, J. Xu, Z. Zhou, S. Mohammed, Q. Wang, D. Lawson, S. Djokic, G. Hou, S. Ding, , S. B. Kutluay

This study identifies tonic activation of the cGAS-STING and IFN pathways in ACE2-positive airway cells as a factor limiting SARS-CoV-2 replication.

bioRxiv · Jan 7, 2024Microbiology

Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

M. Puray-Chavez, K. M. Lapak, T. P. Schrank, J. L. Elliott, D. P. Bhatt, M. J. Agajanian, R. Jasuja, D. Q. Lawson, K. Davis, P. W. Rothlauf, H. Jo, N. Lee, K. Tenneti, J. E. Eschbach, C. Shema Mugisha, , S. B. Kutluay

This study identifies H522 cells as ACE2-negative human cells permissive to SARS-CoV-2 infection, revealing alternative receptor usage and host response mechanisms.

bioRxiv · Mar 1, 2021Microbiology

The translational landscape of SARS-CoV-2 and infected cells

M. Puray-Chavez, K. Tenneti, N. Lee, Y. Wang, H. R. Vuong, Y. Liu, A. Horani, T. Huang, S. P. Gunsten, J. B. Case, W. Yang, M. S. Diamond, S. L. Brody, J. Dougherty, S. B. Kutluay

This study uses ribosome profiling to analyze SARS-CoV-2 and host mRNA translation in infected cells, finding that viral mRNAs are not more efficiently translated than host mRNAs and highlighting unique translational strategies.

bioRxiv · Nov 3, 2020 · PreprintMicrobiology

A facile Q-RT-PCR assay for monitoring SARS-CoV-2 growth in cell culture

C. Shema Mugisha, H. R. Vuong, M. Puray-Chavez, S. B. Kutluay

This paper develops a Q-RT-PCR assay to monitor SARS-CoV-2 growth in cell culture without RNA extraction, showing it can identify inhibitors of viral replication.

bioRxiv · Jun 26, 2020 · PreprintMicrobiology